Scope Poly-pharmacological therapy shapes the gut microbiota (GM) in metabolic syndrome (MetS) patients. The effects of polyphenols poly-medicated MetS patients are unknown. Methods and results A randomized, placebo-controlled, double-blinded, crossover trial (n=50) explored whether a pomegranate extract nutraceutical (PE, 320 mg phenolics/day for 1 month) affected by drug therapy. Considering ...

Microarrays are widely used to evaluate gene expression at the genome scale. However, all too often the importance of data analysis at the level of the individual probe is overlooked. This is a particular problem when trying to detect differences in gene expression levels among genetically unique animals, across inbred animal strains, or among genetically modified animals. Of particular concern...

We describe and prove uniqueness of a natural homomorphism (called the Orchard morphism) between some groups associated to finite sets.

208 NOTICES OF THE AMS VOLUME 51, NUMBER 2 As far as I know, the notion of a quasi-morphism does not have much to do with category theory. This very natural idea underlies several interesting recent developments at the crossroads of algebra, topology, geometry, and dynamics. Other, perhaps better, names currently in use for the same concept are quasi-homomorphism and pseudo-character. Let G be ...

Polycystic Ovarian syndrome (PCOS) is a common endocrine disorder with a global prevalence of 5-10% among women of reproductive age. PCOS is characterized by chronic anovulation, polycystic ovaries, hyperandrogenism, hirsutism, overweight, insulin resistance, and infertility. It is well-known that PCOS is a complex trait similar to type-2 diabetes in which both genetic and environmental factors...

EVOLUTION Correction for “The ABO blood group is a trans-species polymorphism in primates,” by Laure Ségurel, Emma E. Thompson, Timothée Flutre, Jessica Lovstad, Aarti Venkat, Susan W. Margulis, Jill Moyse, Steve Ross, Kathryn Gamble, Guy Sella, Carole Ober, and Molly Przeworski, which appeared in issue 45, November 6, 2012, of Proc Natl Acad Sci USA (109:18493–18498; first published October 22...