UNLABELLED As one of the major organs of the excretory pathway, the kidneys represent a frequent source of radiopharmaceutical uptake in both diagnostic and therapeutic nuclear medicine. The unique organization of the functional tissues of the organ ensures transient changes in suborgan localization of renal activity. Current single-region dosimetric models of the kidneys, however, force the as...

Recent advances in understanding the kidney cancer gene pathways has provided the foundation for the development of targeted therapeutic approaches for patients with this disease. Kidney cancer is not a single disease; it includes a number of different types of renal cancers, each with different histologic features, a different clinical course, a different response to therapy, and different gen...

A 7-year-old boy presented with distended abdomen without any other complaints. A plain abdominal radiograph demonstrated an extremely large soft tissue shadow that occupied right and part of the left hemiabdomen. Ultrasound revealed large hydronephrotic right kidney that occupied whole abdomial cavity without visualization of the left kidney. Dynamic scintigraphy confirmed extreme renal functi...

22 There is little clinical data of how hypertension may influence individuals with nephron 23 deficiency in the context of being born with a single kidney. We recently developed a new rat 24 model (the HSRA rat) that is born with a single kidney and exhibits progressive kidney injury 25 and decline in kidney function with age. We hypothesized that deoxycorticosterone acetate 26 (DOCA)-salt wou...

Introduction:Detecting renal allograft dysfunction early will allow timely diagnosis and treatment. There is no objective recommendation by national kidney societies for glomerular filtration rate (eGFR) estimation in post-transplant setting. 99mTc-DTPA Technetium-99m Diethylene triamine penta acetic acid) renogram can identify early renal dysfunction much before ser...

world kidney day (wkd) is a joint initiative of the international society of nephrology (isn) and the international federation of kidney foundations (ifkf). seven years on from the first campaign, world kidney day (wkd) has turned into a global phenomenon. on march 13, 2014, medical professionals, government officials, the general public, celebrities and patients took action locally. in 2014, t...

-The effects of cis-dichlorodiammine platinum II (DDP) on the intestinal mucosa and the kidney were studied after single and multiple treatments with intervals of 7-45 days. After a single treatment, the jejunal epithelium underwent a transient interruption of cell proliferation followed by a hyperplastic recovery and return to control proliferative rate on Day 7. Subsequent treatments led to s...

1. The tonin concentration of saliva and submaxillary glands was studied in one-clip hypertensive rats with or without the contralateral kidney. 2. Salivary tonin concentration was elevated in one-kidney hypertensive rats, but not in one-kidney normotensive or two-kidney, one-clip hypertensive rats. In contrast, an elevated submaxillary gland tonin concentration was found only in uninephrectomi...