Pro and pre B cells possess the long-term capacity to proliferate in vitro on stromal cells and interleukin 7 (IL-7) and can differentiate to surface immunoglobulin (sIg+) cells upon removal of IL-7 from the cultures. A key event in this differentiation is the extensive cell loss due to apoptosis. Because the proto-oncogene bcl-2 can promote cell survival, we established pre-B cell lines from E...

With the increasing application requirements of spatial information, traditional spatial information techniques can not solve current application problems. As novel technologies that can implement sharing of enormous distributed resource, Grid and Web services provide an effective and efficient way to share and integrate spatial information on the web. Hence, an innovate framework, i.e. Spatial...

The sigma-1 receptor (Sig-1R) is an endoplasmic reticulum membrane protein that involves a wide range of physiological functions. The Sig-1R has been shown to bind psychostimulants including cocaine and methamphetamine (METH) and thus has been implicated in the actions of those psychostimulants. For example, it has been demonstrated that the Sig-1R antagonists mitigate certain behavioral and ce...

Spatial Information Grid is a kind of application grid which tries to connect resources such as computer, data sources, and processing algorithms, and builds a distributed, robust, flexible and powerful infrastructure for geocomputation. It needs a powerful and easy-to-use running environment. In this paper, an autonomic runtime environment for geo-computation is proposed and named SIGRE — the ...

aBooth School of Business, University of Chicago, Chicago, Illinois 60637; bNational Bureau of Economic Research, Cambridge, Massachusetts 02138; cBusiness School, Sichuan University, 610000 Chengdu, China; dFox School of Business, Temple University, Philadelphia, Pennsylvania 19122 ∗Corresponding author Contact: [email protected], http://orcid.org/0000-0002-6488-9158 (J-PD); 149281891@qq....