This paper provides a general method to derive algebraic expressions of genotype frequencies for multiple loci under various mating systems, including random mating, back-crossing, selfing, and full-sib mating. For each mating system, general equations are presented. In the case of three loci, comprehensive tables provide recurrence equations for genotype frequencies under random or self mating...

We evaluated the effects of an enriched environment, based on a paired-choice preference assessment, on both rates of self-injurious behavior (SIB) and percentage of session intervals during which signs of negative affect were displayed by a woman with mental retardation and a mood disorder. Results suggested that SIB and signs of negative affect were highly correlated and that the enriched env...

Submit Manuscript | http://medcraveonline.com Abbreviations: TCP: Tumor Control Probability; NTCP: Normal Tissue Control Probability; LKB: Lyman Kutcher Burman; IGRT: Image Guided Radiation Therapy; IMRT: Intensity Modulated Radiation Therapy; SIB-IMRT: Simultaneous Integrated BoostIMRT; VMAT: Volumetric Modulated Arc Therapy; DA: Double Arc; SA: Single Arc; HT: Helical Tomotherapy; IFP: Improv...

Background and study aims Uptake of flexible sigmoidoscopy screening in the English Bowel Scope Screening (BSS) Programme is low. The aim of this study was to test the impact of a nonparticipant reminder and theory-based leaflet to promote uptake among former nonresponders (previously did not confirm their appointment) and nonattenders (previously confirmed their appointment but did not attend)...

We evaluated the effects of restraint on occurrences of self-injurious behavior (SIB) and adaptive responses exhibited by 2 individuals across eight response-effort conditions: baseline (no restraints); restraint sleeves without stays; restraints with 5, 10, 15, 20, or 25 thin metal stays; and restraints with five thick metal stays. From this analysis, we identified a restraint level for each p...

We describe a sib pair with craniofacial anomalies, micrognathia, Mobius sequence, generalised myopathy, relative macrocephaly, and developmental delay. They appear to have the Carey-Fineman-Ziter syndrome (MIM 254940), which has been reported in only four children, a sib pair and two sporadic cases. This report on an additional affected brother and sister pair supports autosomal inheritance as...

After 50 days of pond culture fewer pike fingerlings (20 to 33 p. 100) were recovered from the mixing of two full-sib families than from isolated families. Growth and survival were influenced by the family effect. Environmental parameters, such as depth and extent of the banks, may also affect growth and survival. Our results indicated that isolating full-sib families and using small, shallow p...

Two widely used affected-sib-pair scoring procedures (the Green and Woodrow [1977] procedure, and the method of forming all possible affected-sib-pairs) are compared with a new method for their relative efficiency in detecting the presence of an HLA-linked disease susceptibility gene. Their relative performance is investigated by extensive computer simulations over a large number of disease tra...