Background/aim: Endothelial dysfunction, tissue damage, inflammation, and microthrombosis are involved in the pathogenesis of pulmonary hypertension (PH), which may be present as a complication of congenital heart diseases. This study aims to identify how indicators of endothelial dysfunction (shear stress), tissue damage (brain natriuretic peptide and troponin T), inflammation (C-reactive prot...

The aim of this study is to find out the correlation of the ventricular size of the brain, as it is estimated using brain computed tomography (CT) scan indexes in patients with normal pressure hydrocephalus (NPH), to: a) the clinical symptoms, and b) the results of cerebrospinal fluid (CSF) shunting procedures. We looked for any predictive value in the estimation of brain CT scan indexes, in pa...

Dendritic integration of excitatory and inhibitory inputs is critical for neuronal computation, but the underlying rules remain to be elucidated. Based on realistic modeling and experiments in rat hippocampal slices, we derived a simple arithmetic rule for spatial summation of concurrent excitatory glutamatergic inputs (E) and inhibitory GABAergic inputs (I). The somatic response can be well ap...

Auditory brainstem responses (ABRs) were studied in 15 adults with suspected normal pressure hydrocephalus (NPH) before and after shunting. The patients were divided into Groups A (shunt-ineffective) and B (shunt-effective). The pre- and postoperative ABRs of each patient were compared with those of 20 normal volunteers, and the relationships between ABRs and certain clinical findings were inve...

To evaluate left-to-right shunts after percutaneous balloon mitral valvuloplasty, we studied 15 consecutive patients by using transesophageal color Doppler flow-imaging system. Transesophageal color Doppler examinations were performed five times in each patient (before valvuloplasty and 1 day, 1 week, 1 month, and 6 months after valvuloplasty). No shunt flow was observed before valvuloplasty. O...

Olgac U, Kurtcuoglu V. Renal oxygenation: preglomerular vasculature is an unlikely contributor to renal oxygen shunting. Am J Physiol Renal Physiol 308: F671–F688, 2015. First published December 10, 2014; doi:10.1152/ajprenal.00551.2014.—The primary aim of this study was to assess the plausibility of preglomerular arterial-tovenous oxygen shunting in the kidney. To this end, we have developed a...

SUMMARY Arterial and mixed venous oxygen tensions were measured in 24 patients following acute myocardial infarction while they were breathing air and 100% oxygen. Total venous admixture and the right-to-left shunt during 100% oxygen breathing were calculated. These data were related to the pulmonary arterial diastolic pressure, the cardiac index, and the central blood volume. Patients with myo...

Highlights. The clinical case report describes the important role of MRI in perinatal diagnosis dural sinus thrombosis, timely verification diagnosis, differential with other vascular and tumor formations brain. Abstract. Dural thrombosis (DST) is a rare congenital anomaly. Ultrasound findings usually mimic intracranial tumors. As result, condition often misdiagnosed its frequency general popul...