objective: for decades, exercise has been considered as a cornerstone for managing diabetes. the current study aimed to determine the effects of short-term exercise on blood glucose, lipids and hba1c in type-2 diabetes mellitus. materials and methods: a total of 61 diabetic patients were randomly selected. later, subjects with capability of doing exercise took part in a special four-week exerci...

Fine airborne respirable particulates less than 10 micrometer (PM10) are considered one of the top environmental public health concerns, since they contain polycyclic aromatic hydrocarbons (PAHs) which are among the major carcinogenic compounds found in urban air. The objective of this study is to assess the genotoxicity of the ambient PM10 collected at 11 urban sites in Jeddah, Saudi Arabia. T...

The genotoxicity of two new anthracycline antitumor antibiotics, aclacinomycin A and marcellomycin, which are potent cytostatic agents similar to Adriamycin and daunomycin, was investigated in various assays. In contrast to Adriamycin and daunomycin, both agents were devoid of mutagenic activity in the Salmonella-microsome assay as well as in a mammalian cell assay using V79 Chinese hamster cel...

In Rajasthan state particularly, textile mills represent an important economic sector. Pali district in Rajasthan has got largest number of textile industries in the State i.e.989 units, mostly engaged in cotton and synthetic textile printing and dyeing. These industries liberate a variety of chemicals, dyes, acids and alkalis besides other toxic compounds like heavy metals, which are known for...

Pesticides widely used in the agricultural market led to an increase quality and yield of crops. However, pesticides are a major concern environment as they also harm non-target creatures, because pesticide resistance, mutagenic carcinogenic effects. In this study, we aimed research potential mutagenicity Karate Zeon which is synthetic pyrethroid insecticide. Salmonella typhimurium assay (Ames ...

The objective of this study was to investigate in a crossover study conducted in human volunteers whether black tea intake modulates the metabolism of heterocyclic amines, consumed in the form of well-cooked beefburgers, as exemplified by the excretion of mutagens in the urine. Mutagens were extracted from urine with blue rayon, and mutagenic activity was determined in the Ames test, in the pre...

Heated food systems contain hundreds of chemical compounds, some being mutagenic and others being antimutagenic. Studies have indicated that foods exposed to drying, frying, roasting, baking, and broiling conditions possess net mutagenic activity as assessed by the Ames/Salmonella/microsome mutagenicity test and the chromosome aberration assay with Chinese hamster ovary (CHO) cells. With the ab...

BACKGROUND The commercial pet-food industry and the market value of the pet industry have increased. Most owners are concerned about their pets' health, and prefer commercial pet foods as their regular diet. This study thus aimed to determine whether a selection of local generic-brand dry canine foods had any potential to promote chronic disease. METHODS Five local, generic-brand, dry canine ...

I N Salmonella typhimurium a cluster of nine genes, behaving as a single operon (AMES and GARRY 1959) specify the enzymes which carry out the ten reactions involved in the biosynthesis of histidine; one of the nine enzymes is bifunctional (LOPER, GRABNAR, STAHL, HARTMAN and HARTMAN 1964). The histidine operon is contained in a linear segment of deoxyribonucleic acid (DNA) estimated by AMES, GOL...