High throughput chemical genetic screens for compounds with specific biological activity in a whole organism are feasible using zebrafish embryos. At least two medium to large scale drug screens have been carried out to date, leading to the identification of compounds that disturb zebrafish development. Chemical genetics using zebrafish embryos may become an important step in the discovery of d...

the solutions of mathematical models for the estimation of the kinetic, and biokinetic parameters of naphthalene, anthracene and pyrene during degradation in surface and subsurface soils are presented in this work. the models were developed using the twin concepts of rate-determining step and steady-state approximation method. they described the biodegradation of single and a mixture of polycy...

We examine the formation of giant elliptical galaxies using their globular cluster (GC) systems as probes of their evolutionary history. The bimodal distributions of GC metallicities in such galaxies are often cited as evidence for the formation of giant elliptical galaxies through mergers involving gas-rich spirals, with the metal-rich GCs forming during the merger process. We explore an alter...

We study the stability of the giant gravitons in the string theory background with NSNS B field. We consider the perturbation of giant gravitons formed by a probe D(8− p) brane in the background generated by D(p− 2)D(p) branes for 2 ≤ p ≤ 5. We use the quadratic approximation to the brane action to find the equations of motion. The vibration modes for ρ , φ and r are coupled, while those of xk’...

Paying off the mortgage, once a widespread rite of passage for homeowners approaching retirement, has become less common in recent years. Concerns are mounting that the increased prevalence of housing debt among older homeowners could compromise financial security in retirement by expanding housing affordability problems, crimping essential nonhousing spending, increasing vulnerability to home ...