either before or during the period of immunosuppression does not necessarily confer protection. This is illustrated by two of our patients. Case reports Case 1. A boy, aged 3 years 5 months, first presented with a history of a progressive petechial rash. Physical examination showed pallor, bruising, and hepatosplenomegaly. A bone marrow aspirate confirmed a diagnosis of acute lymphoblastic leuk...

Researchers at the School of Medicine have discovered an unexpected layer in the regulation of gene expression. The finding will likely disrupt scientists’ understanding of how cells regulate their genes to develop, communicate and carry out specific tasks throughout the body. The researchers found that cellular workhorses called ribosomes, which are responsible for transforming genes encoded i...

We present the case of a 56-year-old male with a history of recurrent follicular lymphoma undergoing chemotherapy with multiple (18)F-FDG PET-CT studies at an outside facility. He developed a painful erythematous, pruritic rash in the left back requiring a visit to the emergency room. He was diagnosed and treated for Varicella zoster infection. He then presented to our imaging center 2 months l...

Although the goal of medicine is to cure disease, effective treatment of the symptoms that the patient notices requires that the clinician identify their underlying cause – namely the diagnosis. Without a diagnosis, clinicians can only palliate the symptoms and hope that the actual disease resolves on its own. The 20th century brought great advances in understanding disease pathophysiology. For...