ammonia is the chief excretory product in fishes. however, non-availability of enough of water in the habitat, may lead to the formation of urea, in fishes. in the present study, the possible role of urea formation to avoid the toxicity of ammonia under water-restricted condition was tested in channa gachua. circulatory urea and ammonia were estimated in the blood of the fishes and glutamate de...

BACKGROUND L-tyrosine is a common precursor for a wide range of valuable secondary metabolites, including benzylisoquinoline alkaloids (BIAs) and many polyketides. An industrially tractable yeast strain optimized for production of L-tyrosine could serve as a platform for the development of BIA and polyketide cell factories. This study applied a targeted metabolomics approach to evaluate metabol...

Ethanol (90%) extract of Ammania baccifera (L.) whole plant (EEAB) was evaluated for possible antister-oidogenic activity in mature female mice ovaries. The ethanol extract at the doses of 100, 200 and 400 mg/kg body weight (i.p) arrested the normal estrus cycle at dioestrus phase and significantly decreased weight of ovaries. The cholesterol and ascorbic acid content in ovaries were significan...

Soil dehydrogenase activity is a good indicator of overall microbial activity in soil, and it can serve as a good indicator of soil condition. However, seasonal changes in soil moisture content may have an effect on soil dehydrogenase activity, making an accurate assessment of soil condition difficult. In this study, we attempted to determine the significance of soil dehydrogenase activity for ...

Understanding the connection between local and global dynamics can provide valuable insights into enzymatic function may contribute to development of novel strategies for enzyme modulation. In this work, we investigated at both (active site) levels Shikimate Kinase (SK) through microsecond time-scale molecular (MD) simulations holoenzyme in product state. Our focus was on wild-type (WT) two mut...

Complementary killing effect of tirapazamine in combination with radiation therapy on cells high aldehyde dehydrogenase activity SAS cell line

The activities of several enzymes of the citric acid and poly-beta-hydroxybutyrate cycles were measured in Rhizobium japonicum 3I1B-143 bacteroids which had been isolated from soybean nodules by sucrose gradient centrifugation. During the period of developing nitrogenase activity, the specific activity of fumarase, hydroxybutyrate dehydrogenase, beta-ketothiolase, and pyruvate dehydrogenase com...

The objectives of this study were to determinethe interactions between two hepatic enzymes and some minerals in the liver of broiler chickens. The study was performed with male and female from 1 to 56 days of age of broiler chickens. Malic acid was added to the water and offered to chickens freely from the start to the end of the experiment with constant concentration. The treatments consisted ...