Chromatin shearing is the first critical step to provide sensitive and reproducible results in chromatin immunoprecipitation (ChIP) experiments. Adaptive Focused Acoustics (AFA) acoustic technology provides precise control over mechanical shearing and thermal control during processing to deliver high quality chromatin for the most sensitive results, in a highly reproducible manner. Optimizing t...

This paper deals with the Saint-Venant’s torsion of thin-walled isotropic nonhomogeneous open elliptical cross section whose shear modulus depends on one curvilinear coordinates which define cross-sectional area beam. The approximate solution problem is obtained by variational method. usual simplification assumptions are used to solve uniform bars cross-sections. An example illustrates applicat...

We present hydro-mechanical measurements that characterize shear on natural fractures in schist, amphibolite, and rhyolite specimens from the enhanced geothermal system (EGS) Collab Project's Experiment 1 2 sites (E1 E2) at Sanford Underground Research Facility. employed a triaxial direct method augmented with X-ray imaging to perform hydroshearing (injection-induced shearing) mechanical sheari...

The discovery and understanding of gecko 'frictional-adhesion' adhering and climbing mechanism has allowed researchers to mimic and create gecko-inspired adhesives. A few experimental and theoretical approaches have been taken to understand the effect of surface roughness on synthetic adhesive performance, and the implications of stick-slip friction during shearing. This work extends previous s...

Background: Musculoskeletal disorders (MSDs) are among the most prevalent pains which could be ignited via material handling. Backpack wearers are among those who may carry heavy loads. Since MSDs mainly originate in school-aged children, students (as the largest group of backpack wearers) are considered more important. The purpose of this study is to design a backpack based on minimization of ...

background; musculoskeletal disorders (msds) are among the most prevalent pains which could be ignited via material handling. backpack wearers are among those who may carry heavy loads. since msds mainly originate in school-aged children, students (as the largest group of backpack wearers) are considered more important. the purpose of this study is to design a backpack based on minimization of ...

We consider the nonaxisymmetric linear theory of radially-stratified disks. We work in a shearing-sheet-like approximation, where the vertical structure of the disk is neglected, and develop equations for the evolution of a plane-wave perturbation comoving with the shear flow (a shearing wave, or “shwave”). We calculate a complete solution set for compressive and incompressive short-wavelength ...

Abstract In the present work, numerical models are developed for shearing and cutting process of advanced high strength steel-blanks which can predict edge morphology in shear effected zone. A damage model, based on modified Mohr-Coulomb fracture surface, is calibrated. To increase predictability models, surface fine-tuned areas corresponding to stress-state cutting, a methodology called Local ...