OBJECTIVES Polysemy is a frequent issue in biomedical terminologies. In the Unified Medical Language System (UMLS), polysemous terms are either represented as several independent concepts, or clustered into a single, multiply-categorized concept. The objective of this study is to analyze polysemous concepts in the UMLS through their categorization and hierarchical relations for auditing purpose...

Wind-borne pollinating wasps (Agaonidae) can transport fig (Ficus sp., Moraceae) pollen over enormous distances (> 100 km). Because of their extensive breeding areas, Neotropical figs are expected to exhibit weak patterns of genetic structure at local and regional scales. We evaluated genetic structure at the regional to continental scale (Panama, Costa Rica, and Peru) for the free-standing fig...

ABSTRACT: Bi-molecular reactions can affect the transport of air pollutants in urban street canyons. In numerical simulations, we need to evaluate the correlation between the concentrations of the reactants to know the reaction rate. In this paper, we examine the effects of the subgrid scale (SGS) on the reaction rate in large-eddy simulations (LESs). LESs coupled with an SGS variance model are...

In this analysis, we attempt to understand how monoecy and dioecy drive spatial genetic structure (SGS) in plant populations. For this purpose, plants of the genus Ficus were used as a comparative model due to their particular characteristics, including high species diversity, variation in life histories, and sexual systems. One of the main issues we assessed is whether dioecious fig tree popul...

Various kinds of stress on human cells induce the formation of endogenous stress granules (SGs). Human Argonaute 2 (hAgo2), the catalytic core component of the RNA-induced silencing complex (RISC), can be recruited to SGs as well as P-bodies (PBs) indicating that the dynamic intracellular distribution of hAgo2 in SGs, in PBs or at other sub-cellular sites could be related to the efficiency of t...

This work is devoted to exploring a new procedure to develop subgrid-scale (SGS) models in the context of large-eddy simulation (LES) of a passive scalar. Starting from the Noll’s formula (Noll 1967), the concept of an optimal estimator is first used to determine an accurate set of parameters to derive a SGS model. The SGS model is then defined as a surrogate model built from this set of parame...

High Reynolds number turbulent flows of incompressible fluids in plane channels and annuli are simulated using a finite difference procedure which integrates the NavierStokes equations in time and in three-dimensional space. This paper describes the finite difference procedure and the subgrid scale (SGS) motion model. The model differs from earlier ones in the following points. The finite diffe...

In response to environmental stress and viral infection, mammalian cells form foci containing translationally silenced mRNPs termed stress granules (SGs). As aggregates of stalled initiation complexes, SGs are defined by the presence of translation initiation machinery in addition to mRNA binding proteins. Here, we report that cells infected with poliovirus (PV) can form SGs early that contain ...

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Ribonucleoprotein (RNP) granules transport, store, or degrade messenger RNAs, thereby indirectly regulating protein synthesis. Normally, RNP granules are highly dynamic compartments. However, because of aging or severe environmental stress, RNP granules, in particular stress granules (SGs), convert into solid, aggregate-like inclusions. There is increasing evidence that such RNA-protein inclusi...