Among non-communicable diseases diabetes is one of the common multifactorial metabolic X disease responsible for huge mortality and economic burden worldwide. Liver most important control organ body serum ferritin regarded as indicative diabetes. As studies pertaining to combined incidence ferretin, b. sugar enzymes are scarce. So present study was aimed describe correlation if any between diab...

Topography affects the fraction of scene components canopy and background, resulting in observed reflectance distortion. Modeling over rugged terrain needs to account for topographic effects. For this purpose, existing models greatly increased mathematical complexity while improving description crown structure, which dramatically decreased computational efficiency so as limit their universal ap...

Purpose: To evaluate the hepatoprotective activity of aqueous-ethanol (30:70 %) extract of Alhagi maurorum Boiss. (Leguminosae) whole plant against paracetamol-induced liver injury in experimental rabbits. Methods: Aqueous-ethanol extract of Alhagi maurorum at doses of 250 mg/kg and 500 mg/kg body weight, p.o., was administered for 7 days in paracetamol (2 gm/kg, s.c.) intoxicated rabbits and c...

Doxorubicin (DOX) induces oxidative stress leading to cardiovascular abnormalities. Green tea extract (GTE) is reported to possess antioxidant activity mainly by means of its polyphenolic constituent, catechins. Our study was aimed to find out the effect of GTE (100 mg/kg / day p.o. for 28 days) on DOX induced (3 mg/kg, IP on days 1, 7, 14, 21, 28) cardiovascular abnormalities in rat heart. DOX...

OBJECTIVE To evaluate and validate, in our laboratory, the essay of myocardial infarction induced by isoproterenol in rats by means of analysis of hematological, biochemical, oxidative stress markers and histopathological parameters. METHODS Thirty young, male, Wistar rats (145 to 230 g) were randomly allocated in two groups: Sham group, which underwent a virtual myocardial infarction inducti...

In the present study, we studied the effect of Genistein against the hepatotoxicity induced by N-nitrosodiethylamine (NDEA). NDEA is present in almost all kinds of food stuff and has been reported to be a hepatocarcinogen. The male rats were exposed to NDEA (0.1 mg/mL) dissolved in drinking water separately and along with 25, 50, 100 mg/mL of Genistein for 21 days. The activities of serum gluta...

The present investigation aims at assessing the hepatoprotective effect of triterpene fraction isolated from the stem bark of Wrightia tinctoria (containing lupeol, β-amyrin and β-sitosterol) on CCl4-induced hepatotoxicity in the rat. CCl4 (1.5 mg/kg, i.p) is a potent hepatotoxic agent which causes peroxidative degeneration of membrane lipids with the potential outcome of fatty degeneration. Th...

Hitherto unknown effects of Pyrroloquinoline quinone (PQQ) in 6-n-propyl-2-thiouracil (PTU)induced oxidative stress and lipid peroxidation were investigated in adult mice. Animals received either PTU (0.05% in drinking water) alone for 5 weeks or PTU + three different concentrations of PQQ, after which alterations in tissue lipid peroxidation (LPO) and in enzymatic activities of superoxide dism...

Formocresol applied to vital pulp tissue may be absorbed systemically. The possible effect of the systemic absorption of formocresol is unknown. The purpose of this project was to determine the acute toxic effect of systemically administered formocresol. Two dogs were anesthetized and Buckley’s formocresol was administered i.v. a t doses of 0.05 and 0.1 5 ml/kg respectively. Blood pressure and ...