Abstract We present a numerical investigation into the stochastic parameterisations of Primitive Equations (PE) using Stochastic Advection by Lie Transport (SALT) and Forcing (SFLT) frameworks. These frameworks were chosen due to their structure-preserving introduction stochasticity, which decomposes transport velocity fluid momentum drift parts, respectively. In this paper, we develop new cali...

Purpose - to determine the presence of genetic determinism on part thrombophilia and angiogenesis candidate genes, their prognostic value in development preeclampsia (РЕ) women with retrochorial hematoma (RCH). Materials methods. The course pregnancy was analyzed 137 threat miscarriage aged 20 47 years (the Group 1 60 patients RCH, 2 77 without hematoma). Additionally, polymorphisms vascular en...

Purpose To evaluate the angiogenic properties of corneal derived mesenchymal stromal cells (Co-MSC). Methods Co-MSCs were extracted from human cadaver, and wild-type (C57BL/6J) and SERPINF1-/- mice corneas. The MSC secretome was collected in a serum-free medium. Human umbilical vein endothelial cell (HUVEC) tube formation and fibrin gel bead assay (FIBA) sprout formation were used to assess t...

The prognosis of gastric cancer with peritoneal metastasis has not improved. Despite many promising studies, gene therapy has limited clinical application because of the lack of suitable vector systems to enable selective gene transduction to tumor cells. The aim of this study was to clarify whether gene therapy targeted to peritoneal mesothelial cells (PMCs) can inhibit peritoneal disseminatio...

Blood vessel formation requires the integrated regulation of endothelial cell proliferation and branching morphogenesis, but how this coordinated regulation is achieved is not well understood. Flt-1 (vascular endothelial growth factor [VEGF] receptor 1) is a high affinity VEGF-A receptor whose loss leads to vessel overgrowth and dysmorphogenesis. We examined the ability of Flt-1 isoform transge...

OBJECTIVE To investigate the potential value of maternal serum placental growth factor (PlGF) and soluble fms-like tyrosine kinase-1 (sFlt-1) at 35-37 weeks' gestation in the prediction of delivery of small-for-gestational-age (SGA) neonates, in the absence of pre-eclampsia (PE). METHODS This was a screening study in singleton pregnancies at 35-37 weeks, including 158 that delivered SGA neona...

Preeclampsia (PE) is a life-threatening pregnancy complication for the mother and fetus. High concentrations of human chorionic gonadotrophin (hCG) soluble fms-like tyrosine kinase-1 (sFLt-1) during may have role in pathophysiology PE. Swimming Exercise (SE) one physical activities recommended pregnant women carries minimal risk. This study aimed at analyzing interaction between conditions rats...

The objective: to assess and establish the relationships between Doppler blood flow indicators in uterine arteries, angiogenesis factors hormones of mother-placenta-fetus system pregnant women with arterial hypertension I-II degree.Materials methods. A prospective study 88 at 11–12 weeks gestation was carried out: 61 chronic (CH) I–II degree (main group) 27 healthy physiological pregnancy (cont...