نتایج جستجو برای: sex steroid binding protein

تعداد نتایج: 1667173  

Journal: :The Journal of Experimental Medicine 1995
I M Adcock S J Lane C R Brown T H Lee P J Barnes

Glucocorticosteroids are a very effective treatment for asthma and other chronic inflammatory diseases. However, a small proportion of patients is resistant to the therapeutic effects of glucocorticoids. Pharmacokinetic and ligand binding studies suggest that the molecular abnormality in steroid resistance lies distal to nuclear translocation. We have previously reported that there is a decreas...

Journal: :Clinical chemistry 1989
L A Molnar N Dhirani K Tran W A McBlain

Accurate quantification of estrogen receptor (ER) is essential for optimal clinical characterization of individual cases of breast cancer. If breast tumors are mishandled, the relatively labile ER protein may lose its steroid-binding capacity (become inactivated) and not be measurable by the routine steroid-binding assay. We tested whether the commercial enzyme immunoassay of Abbott Laboratorie...

Journal: :شیلات 0
سیده مرضیه حسینی خواه کارشناس ارشد مهندسی منابع طبیعی- شیلات دانشگاه تهران، ایران، باقر مجازی امیری استاد گروه شیلات دانشکدة منابع طبیعی دانشگاه تهران، ایران، غلامرضا رفیعی استاد گروه شیلات دانشکدة منابع طبیعی دانشگاه تهران، ایران، مهرداد فرهنگی دانشیار گروه شیلات دانشکدة منابع طبیعی دانشگاه تهران، ایران سید مهیا موسوی کارشناس ارشد مهندسی منابع طبیعی- شیلات دانشگاه تهران، ایران

to study the effect of dietary animal and plant lipids on gonadal differents and sex steroid hormones levels of blood in rainbow trout (oncorhynchus mykiss), the four diets was formulated based on 15% fat. the control uses 100% oil, fish oil was treated in the first, second and third respectively 25% and 75% fish oil, soybean oil, canola and cotton were used. after six weeks of feeding fish wit...

Journal: :Journal of Comprehensive Pediatrics 2023

Background: Nephrotic syndrome (NS) is a common glomerular disease in children, for which there are currently no noninvasive markers predicting responsiveness to steroid treatment. Objectives: This study aimed analyze the relationship between clinical-laboratory presentations and subsequent response therapy evaluate role of urinary vitamin D binding protein (uVDBP) as predictor resistance (SR)....

Elham Afiatjou Soghra Khabnadideh Zahra Rezaei,

       The binding of drugs by plasma proteins is an important phenomenon, because it influences the size of the free fraction of the drugs in plasma. In this study the influence of dipyridamole (DP) on the protein binding of propranolol (PL) and PL on the protein binding of DP were studied alone and in the presence of nicotine (NC).        The equilibrium dialysis was employed for protein bin...

2013
Antoine Abrieux Stéphane Debernard Annick Maria Cyril Gaertner Sylvia Anton Christophe Gadenne Line Duportets

Most animals including insects rely on olfaction to find their mating partners. In moths, males are attracted by female-produced sex pheromones inducing stereotyped sexual behavior. The behaviorally relevant olfactory information is processed in the primary olfactory centre, the antennal lobe (AL). Evidence is now accumulating that modulation of sex-linked behavioral output occurs through neuro...

Journal: :Journal of animal science 1981
C E Rexroad

Two experiments were conducted to study the role of estradiol and progesterone in regulating steroid binding sites in sheep uterine myometrium. Exogenous estradiol increased the concentration of estradiol binding sites in nuclei and subsequently increased the total cell content of estradiol binding sites. Estradiol increased the number of progestogen binding sites (promegestone binding) and may...

Journal: :The Journal of steroid biochemistry and molecular biology 2000
H Hodgert Jury T R Zacharewski G L Hammond

Human sex hormone-binding globulin (SHBG) binds sex steroids with high affinity. In plasma, the number of SHBG steroid-binding sites far exceeds the molar concentrations of sex steroids, and will accommodate other ligands such as phytoestrogens and fatty acids. We have therefore developed a screening assay to identify ligands for SHBG, which exist in our diet or environment. This assay allows t...

Journal: :The Journal of clinical investigation 1997
S C Lin T Yamate Y Taguchi V Z Borba G Girasole C A O'Brien T Bellido E Abe S C Manolagas

Both estrogen and androgen exert their antiosteoporotic effects, at least in part, by inhibiting IL-6 production, thereby suppressing osteoclastogenesis. Several observations, however, suggest that besides increased IL-6 production, sensitivity of the osteoclastogenic process to this cytokine is altered after ovariectomy. Based on this and evidence that the ligand-binding subunit of the IL-6 re...

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