نتایج جستجو برای: severe combined immune deficiency
تعداد نتایج: 1039889 فیلتر نتایج به سال:
Major histocompatibility complex (MHC) class II deficiency is a rare autosomal recessive form of primary immunodeficiency disorder (PID) characterized by the deficiency of MHC class II molecules. This deficiency affects the cellular and humoral immune response by impairing the development of CD4+ T helper (Th) cells and Th cell-dependent antibody production by B cells. Affected children typical...
Vitamin D is an immune modulator hormone with an anti-inflammatory effect. In this study the potential association between vitamin D and risk of Covid-19 disease were examined. Data of worldwide mortality rate of Covid-19 pandemic according to geographical distribution in 108 countries were analyzed. The results shows Covid-19 outbreaks and particularly mortality exhibit a decreasing North-Sout...
primary immunodeficiencies constitute a group of highly complex congenital disorders most of which are characterized by a very poor prognosis. allogeneic hematopoietic stem cell transplantation (hsct) has become an established curative treatment approach in many of these disorders, which may be permanently corrected. in this presentation basic and practical aspects of hsct are presented, with a...
In this paper, we report an inhibitor antibody to factor XI (FXI) in a woman with severe inherited FXI deficiency, induced by FXI present in an Rh immune globulin preparation. The patient is homozygous for the Glu117Stop mutation, associated with a FXI level of less than 1 U/dL. Unlike all previously described patients with severe FXI deficiency and an inhibitor, the patient had never been expo...
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