نتایج جستجو برای: sesquiterpene lactone fraction
تعداد نتایج: 157727 فیلتر نتایج به سال:
2α-Acetoxy-15-acetylartemisiifolin, a new Anti-trypanosomal Sesquiterpene Lactone from Mikania guaco
Artemisinin (ART) is a sesquiterpene lactone and popular malaria drug used in many parts of the world. Artesunate (ARTS) semi-synthetic derivative ART with improved pharmacokinetic properties. However, half-life ARTS less than an hour vivo. The analysis this vitro different solvent systems using LC-MS/TOF showed solvent-driven breakdown. breakdown formed several derivatives, including dihydroar...
Triple negative breast cancer (TNBC) is a highly metastatic cancer among the breast cancer subgroups. A thorny issue for clinical therapy of TNBC is lack of an efficient targeted therapeutic strategy. We previously created a novel sesquiterpene lactone analog (named DETD-35) derived from plant deoxyelephantopin (DET) which exhibits potent effects against human TNBC MDA-MB-231 tumor growth in a ...
Helicobacter pylori is associated with various diseases of the upper gastrointestinal tract, such as gastric inflammation and duodenal and gastric ulcers. The aim of the study was to assess anti-H. pylori effects of the sesquiterpene lactone dehydrocostus lactone (DCL) from Magnolia sieboldii leaves, compared to commercial pure DCL, two previously known sesquiterpene lactones (costunolide and p...
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