The biotransformation of dihydro-epi-deoxyarteannuin B (compound 1) was investigated by using suspension-cultured cells of Averrhoa carambola. One novel sesquiterpene, 7α-hydroxy-dihydro-epideoxyarteannuin B (compound 2, 29.02%), and one known sesquiterpene, 3-α-hydroxy-dihydro-epideoxyarteannuin B (compound 3, 23.26%), were obtained upon the addition of the substrate (compound 1). All the biot...

Trypanocidal constituents of Pogostemon cablin were investigated. Activity guided isolation of the acetone extract resulted in isolation of three new sesquiterpene hydroperoxides 1-3, together with a known sesquiterpene, patchouli alcohol (4). In vitro minimum lethal concentrations of the hydroperoxides 1-3 against epimastigotes of Trypanosoma cruzi were 0.84 microM (1), 1.7 microM (2) and 1.7 ...

Anna Aiello, Ernesto Fattorusso*, and Marialuisa Menna Dipartimento di Chimica delle Sostanze Naturali, Via D. Montesano 49, 1-80131 Napoli, Italy Z. Naturforsch. 48b, 209-212(1993); received September 18. 1992 Spongidae, Smenospongia aurea, Sesquiterpene, Antibiotic, NM R Spectra A new sesquiterpene phenol, containing the rather uncommon chlorine atom, was isolated from a sample of Smenospongi...

Chemical investigation of the Bulgarian species Tanacetum. parthenium, T. millefolium, T. achilleifolium, T. corymbosum and T. macrophyllum afforded in addition to 24 known sesquiterpene lactones a new 12, 8-eudesmanolide 22. Besides, four known highly oxigenated terpenoids and a new keto-diol 30 of the rare iphionane skeleton were also isolated. The structures were elucidated on the basis of t...