Cefoperazone was compared with penicillin against Streptococcus pneumoniae, gentamicin against Escherichia coli, and ampicillin and chloramphenicol against Haemophilus influenzae in the therapy of experimental meningitis in rabbits. Meningitis was produced by intracisternal inoculation into cerebrospinal fluid, and all antibiotics were administered intravenously over 8 h in dosages that would a...

Subtilin is an antibiotic extracted from the cells of a particular strain of Bacillus subtiliws.3" It is a low molecular weight substance that dialyzes through collodion membranes, is sensitive to light and alkali, and has the structure of a peptide. Subtilin is soluble to at least 30 per cent in saltfree acidified solution. The solubility in acid solution is markedly decreased by the presence ...

Streptococcus pneumoniae is the most common micro-organism which causes respiratory tract diseases affecting all age groups. The increasing frequency of pneumococcal strains resistant to penicillin has been reported all over the world. The emergence of drug-resistant strains threatens to complicate the management of respiratory infections due to pneumococcus. Atatürk Chest Disease and Thoracic ...

In an area with a high incidence of gonorrhoea, where strains of Neisseria gonorrhoeae having a reduced sensitivity to penicillin in vitro are common, there is an urgent need for effective routine therapy. Furthermore, when local conditions are such that diagnosis and therapy are in the hands of personnel with a limited training, treatment must be both simple and easy to administer. When the fo...

1. The concentrations of penicillin G which (a) reduced the net rate of multiplication, (b) exerted a net bactericidal effect, and (c) killed the organisms at a maximal rate, have been defined for a total of 41 strains of alpha- and beta-hemolytic streptococci, Staphylococcus aureus and Staphylococcus albus, Diplococcus pneumoniae, and the Reiter treponoma. 2. The concentration which killed the...

renal dysfunction is a risk marker in patients who candidate for coronary artery bypass graft (cabg). renal disorder is associated with prolonged stays in intensive care unit and hospital, morbidity and mortality. aim of this study is specific evaluation of association between preoperative creatinine (cr) with atrial fibrillation (af) after elective off-pump cabg in non-diabetic male patients w...