During the past decade there has been an increasing interest shown in the study of electrolyte balance. Magnesium, however, has played a minor r81e in these studies. There are perhaps two reasons for this; first, that serum magnesium levels remain fairly constant and, second, that magnesium determinations require special technique and equipment and are time-consuming procedures as well. There h...

BACKGROUND Randomized trials have reached different conclusions as to whether magnesium is a useful adjuvant to postoperative analgesia. METHODS We performed a comprehensive search (electronic databases, bibliographies, all languages, to 4.2006) for randomized comparisons of magnesium and placebo in the surgical setting. Information on postoperative pain intensity and analgesic requirements w...

objective: the aim of this study was to evaluate the effect of zinc and magnesium supplementation on glycemic control and serum insulin in type 2 diabetic patients. materials and methods: in this randomized clinical trial 70 diabetic patients who referred to yazd diabetes center were selected. subjects received 500 mg/day magnesium oxide or 100 mg/day zinc sulfate randomly for 8 weeks. at the s...

DEAR EDITOR, We read with great interest, the published article entitled “relationship of serum magnesium and Vitamin D levels in a nationally-representative sample of Iranian adolescents; the CASPIAN-III study” by Kelishadi et al. They aimed, to assess the association of serum magnesium and Vitamin D (25(OH) D) levels in 330 students, aged range from 10 to 18 years. At this study, they found t...

BACKGROUND Although cross-sectional studies have suggested a relationship between proton pump inhibitor (PPI) use and hypomagnesemia, no large-scale cohort study has been conducted to date. Here, we examined the changes in serum magnesium levels in response to PPI use. We hypothesized that PPI use might change the serum magnesium concentration. METHODS Of the 2,892 patients hospitalized for p...

BACKGROUND Low serum magnesium has been linked to increased risk of atrial fibrillation (AF) after cardiac surgery. It is unknown whether hypomagnesemia predisposes to AF in the community. METHODS AND RESULTS We studied 3530 participants (mean age, 44 years; 52% women) from the Framingham Offspring Study who attended a routine examination and were free of AF and cardiovascular disease. We use...

OBJECTIVE Migraine is known as one of the most disabling types of headache. Among the variety of theories to explain mechanism of migraine, role of serum magnesium is of great importance. Serum magnesium, as a pathogenesis factor, was considerably lower in patients with migraine. We established this study to see if serum ionized magnesium, not its total serum level, was different in migraineurs...

Low magnesium intake has been implicated in a broad range of cardiometabolic conditions, including diabetes, hypertension, and cardiovascular disease. Dietary magnesium and total body magnesium status are widely used but imperfect biomarkers in serum magnesium. Despite serum magnesium’s limitations, it is nevertheless observed to be lower in those with cardiometabolic disease than in generally ...

BACKGROUND Preliminary evidence suggests that magnesium wasting occurs in patients who are treated with epidermal-growth-factor receptor (EGFR)-targeting antibodies for colorectal cancer. The mechanism of this side-effect is unknown, and if all or a subset of patients are affected is also unclear. We aimed to assess the incidence, characteristics, and predictive factors of magnesium wasting dur...