background kawasaki disease (kd) is a vasculitis affecting multi-organ systems including liver and kidneys. kd is diagnosed by some clinical criteria including sterile pyuria, microscopic hematuria, proteinuria due to renal involvement, liver abnormalities manifesting as abnormal liver function tests, gallbladder hydrops, and hypoalbuminemia. objectives the aim of the study was to determine the...

Aim. In this study, we aimed to investigate the effects of febuxostat, a novel inhibitor of xanthine oxidase (XO), on renal damage in streptozotocin- (STZ-) induced diabetic rats. Methods. Diabetes was induced by the intraperitoneal injection of STZ in male Sprague-Dawley rats. Sham-injected rats served as controls. The control and diabetic rats were treated with and without febuxostat for 8 we...

Applications The Eimer and Amend Photoelectric Colorimeter can be used wherever "visual" colorimetric methods are employed. Published determinations with this type of instrument include the following: Fluorides, HCN (turbidity), Blood sugar, Urine sugar, Blood creatinine, Cholesterol, Hemoglobin, Indican, Bilirubin, Nitrogen, Blood protein, Urine protein, Spinal fluid protein, Urea, Creatine, G...

BACKGROUND Although advancements have been made in the management of thalassemic patients, many unrecognized complications have emerged, such as renal abnormalities. AIM To measure serum levels of cystatin-C and β-2 microglobulin in children with beta-thalassemia major (β-TM) and investigate their significance as early markers of glomerular and tubular dysfunctions. SUBJECTS AND METHODS The...

BackgroundLoop diuretics are the main treatment for patients with acute heart failure, but associated neurohormonal stimulation and worsening renal function do not improve long-term outcomes. Antagonists to arginine vasopressin may provide an alternative strategy avoid these effects. The AVANTI study will investigate efficacy safety of pecavaptan, a novel, balanced dual-acting V1a/V2 antagonist...

the objective of this study was to determine and compare cystatin c changes before and after radiotherapy in patients with stomach cancer who were candidate for radiotherapy. this study was conducted as a prospective cohort one. eighteen patients with definite diagnosis of stomach cancer under treatment by radiotherapy who presented to radiotherapy-oncology center of imam hossein hospital, tehr...

Recent studies have shown that renal ischemia-reperfusion injury can detrimental effects on distant organs such as the brain, liver and lungs. In this study, we aimed to investigate of pancreatic functions.
 Materials Methods. Twenty four male adult Wistar rats were divided into groups. Sham control group animals not given any medications. Animals in groups 3 4 treated with epidural bupiva...

conclusions acute acalculous gallbladder disease is a rare complication of hav infection which should be suspected in any child with right upper quadrant abdominal pain, tenderness, and mass which can lead to surgical emergency in rare conditions. introduction acute hepatitis a virus (hav) infection is common in the developing countries among children, but hydrops of gallbladder due to hepatiti...

BACKGROUND Monoclonal antibodies targeting vascular endothelial growth factor (VEGF), such as bevacizumab, are administered intravitreally for the treatment of wet or exudative age-related macular degeneration (ARMD). Systemic use of bevacizumab has been linked to a wide range of renal adverse effects including proteinuria and hypertension. CASE PRESENTATION We present the case of a 77-year-o...