Ovarian serous neoplasms can have morphologic overlap with malignant mesothelioma. The distinction is clinically important, yet most studies have failed to identify immunostains that reliably distinguish these 2 tumor types. Recently, transcription factor PAX8 was shown to be a sensitive and relatively specific marker for Müllerian tumors. In addition, some studies suggest that h-caldesmon is s...

Chemotherapy (CT) resistance in ovarian cancer is broad and encompasses diverse, unrelated drugs, suggesting more than one mechanism of resistance. We aimed to analyze the gene expression patterns in primary serous epithelial ovarian cancer (EOC) samples displaying different responses to first-line CT in an attempt to identify specific molecular signatures associated with response to CT. Initia...

Central serous chorioretinopathy developed in 2 cases of retrobulbar neuritis during systemic treatment with corticosteroids. Fluorescein angiography confirmed leakage surrounded by central serous detachment of the retina. In one case the central serous chorioretinopathy recurred 3 times during 3 separate courses of treatment. Spontaneous recovery accompanied a reduction in steroid treatment to...

We describe a case of a solid variant of serous cystadenoma of the pancreas. The preoperative examination results led to a diagnosis of a nonfunctional pancreatic islet cell tumour, and the patient underwent a pylorus-preserving pancreaticoduodenectomy. The tumour was diagnosed as a solid variant of serous cystadenoma by histopathological examination. Solid variant of serous cystadenoma of the ...

To the Editor, The tubarial salivary glands: A potential new organ at risk for radiotherapyRadiotherapy and OncologyVol. 154PreviewThe gland system, with its three paired major glands roughly 1000 minor spread throughout aerodigestive tract submucosa, has been described in detail [1–4]. Its serous, mucous or mixed exocrine acini produce saliva required mastication, swallowing, digestion, tastin...

purpose: to present a case of bilateral idiopathic central serous chorioretinopthy (icsc) complicated by bullous serous retinal detachment (rd). case report: a 26-year old female suffered from acute loss of vision in the both eyes. best spectacle-corrected visual acuity was 1/10 ou. the examination of anterior segment was unremarkable and a mild vitreous reaction was noted. dilated fundus exami...

Serous borderline ovarian tumors have a favorable prognosis, and recurrences are uncommon. The factors influencing recurrence are not fully understood. Epithelial inclusions are identified in serous borderline ovarian tumors and are traditionally referred to as epithelial implants, which often show epithelial proliferation. We investigated whether the presence of epithelial implant and epitheli...

The present study was conducted to describe the histological features of parotid and submandibular salivary glands of European hamster. The glands samples were obtained from five adult males and microscopic slides were prepared using routine histological technique. The results showed that these glands divide in lobes associated with the ducts. The parotid was a typical serous gland, but the sub...

While the paradigm that malignancies arise through a stepwise progression from benign precursors has been established for many malignancies, it remains unclear if this holds true for ovarian cancer. Serous ovarian carcinomas are the predominant clinically important subtype and it has been widely believed that some or all of these arise from precursors derived from the ovarian surface epithelium...