PURPOSE To evaluate and present our initial results of a new marker (hemosiderin) for mammary sentinel lymph node identification in an experimental model. METHODS Skins mapped like a lymphatic duct draining to the axilla in patients submitted to breast biopsy, in our mastology service, stimulated us to try it in an animal model (female dogs). Our theory was that some blood derivate (hemosider...

378 www.thelancet.com/oncology Vol 15 April 2014 tumour is malignant melanoma. Likewise, sentinel lymphadenectomy is not useful for staging disease in the management of atypical Spitz tumours because metastases from these tumours are not prognostic. The results of Lallas and colleagues’ study establish that sentinel lymph node metastasis is not of diagnostic or prognostic signifi cance in patie...

................................................................................................................................... 1 LIST OF ABBREVIATIONS ......................................................................................................... 4 BACKGROUND AND INTRODUCTION ................................................................................... 5 The ‘black cancer’:...

Is there a role for sentinel lymph node (SLN) biopsy in the management of sarcoma? Sentinel node biopsy has dramatically changed the management of melanoma and breast cancer, helping surgeons avoid radical lymphadenectomies in node negative patients who would previously have undergone a more morbid operation with little benefit, or remained pathologically unstaged. Many investigators have explo...

................................................................................................................................... 1 LIST OF ABBREVIATIONS ......................................................................................................... 4 BACKGROUND AND INTRODUCTION ................................................................................... 5 The ‘black cancer’:...

BACKGROUND The aim of this pilot trial was to study the feasibility of sentinel node percutaneous preoperative gamma probe-guided biopsy as a valid preoperative method of assessment of nodal status compared to surgical sentinel lymph node biopsy. MATERIAL/METHODS This prospective study enrolled 10 consecutive patients without evidence of axillary lymph node metastases at preoperative imaging....

AIM The sentinel lymph node biopsy (SLNB) was firstly introduced by Giuliano and co. in 1994 for the treatment of breast cancer; in comparison to the axillary lymph node dissection (ALND), the sentinel lymph node biopsy has shown both a lower morbidity and acceptable distance results. We want to show that this technique is reliable and should be used routinely in selected cases. MATERIALS OF ...