1 “Grigore T. Popa” University of Medicine and Pharmacy, School of Pharmacy, Iaşi, Romania 2 “Ion Ionescu de la Brad” University of Agricultural Sciences and Veterinary Medicine, School of Veterinary Medicine, Iaşi, Romania ABSTRACT. The purpose of the study was to assess the effect of selenium supplementation on serum amylase, lactate dehydrogenase (LDH) and alkaline phosphatase (ALP) activiti...

The Selenium and Vitamin E Cancer Prevention Trial (SELECT) was conducted to assess the efficacy of selenium and vitamin E alone, and in combination, on the incidence of prostate cancer. This randomized, double-blind, placebo-controlled, 2 × 2 factorial design clinical trial found that neither selenium nor vitamin E reduced the incidence of prostate cancer after seven years and that vitamin E w...

The effect of dietary supplementation of selenium in an organic form on performance, carcass traits and selenium content in tissues of broiler cockerels Ross 308 was studied. The soya-wheat-maize diet contained 50 mg vitamin E/kg. The experiment was conducted on 810 straight-run broiler cockerels randomly divided into 3 groups: group I – control, without selenium supplement; experimental group:...

Magnesium and selenium belong to important bioelements. Magnesium is the second most abundant intracellular macroelement, which takes part in the metabolism of carbohydrates, nucleic acids, protein and lipids. Selenium is an essential microelement, whose deficit has been stated in many different pathological states. Much research on safe and effective selenium supplementation has been performed...

BACKGROUND Patients with chronic autoimmune thyroiditis have impaired health-related quality of life. The thyroid gland has a high selenium concentration, and specific selenoprotein enzyme families are crucial to immune function, and catalyze thyroid hormone metabolism and redox processes in thyroid cells. Previous randomized controlled trials have found that selenium supplementation decreases ...

The aim of this trial was to compare the effect of supplementation of goats with different forms of selenium on the metabolism of their kids at the time of weaning. The experiment was performed with 45 kids of mothers supplemented with various forms of selenium. Group C was control while the other four groups were supplemented with selenium for six weeks before (0.3 mg/goat/day) and after partu...

The experiment was conducted to study productive, physiological and immunological parameters in Bandarah local chicks as affected by dietary organic selenium (SelPlexTM). All chicks were used in the present work produced from females and males fed diets with 0.0, 0.1, 0.2 and 0.3 mg Se / kg diet in the form of selenium yeast (Sel-PlexTM). Two hundred unsexed oneday old chicks (50 chicks per par...

Adriamycin-induced cardiomyopathy in rabbits was produced by intravenous injections of the drug with a short therapeutic schedule (3 mg/kg body wt administered as four intermittent doses). Animals receiving selenium supplementation of Adriamycin showed preservation of the normal pattern of the heart histologic picture. The protective effect of selenium was accompanied by increased selenium leve...

Over the years, evidence has been accumulating [1, 2] that selenium is an essential nutrient in animals, preventing various serious deficiency diseases. On the other hand, no such firm proof for the need of selenium in human nutrition has been established, although several instances of beneficial effects as a result of selenium supplementation of human diet have been reported [3-5]. Although va...

Although many studies have investigated the metabolism of selenium and arsenic in hyperaccumulating plants for phytoremediation purposes, few have explored non-hyperaccumulating plants as a model for general contaminant exposure to plants. In addition, the result of simultaneous supplementation with selenium and arsenic has not been investigated in plants. In this study, Chlorophytum comosum, c...