This work presents a novel, two-scale model of viral infection evolution in a cell population taking into account immunological response based on Interferon-β. Infection dynamics is analyzed on a population level, using standard compartmental approach and on a intracellular level, describing biochemical processes taking place inside cells during infection. Additionally, an optimization problem ...

Currently, the laboratory diagnosis of Zika virus (ZIKV) infection is primarily through the detection of ZIKV RNA or antibodies against ZIKV proteins. The detection of viral RNA is highly sensitive and specific, but periods of viremia and viruria are brief, limiting the utility of ZIKV RNA assays. Instead, most ZIKV infections are diagnosed serologically, using an IgM antibody capture enzyme-li...

Here we report the occurrence of pale yellowish perivascular preretinal dots in 12 patients with ocular syphilis. A case series of these patients was examined between March and October 2012 at the Uveitis Sector of Universidade Federal de São Paulo. After diagnostic confirmation of syphilis, fundus photographs and optical coherence tomography (OCT) were performed to verify the localization of t...

Canola (Brassica napus L. and B. rapa L.), is one of the major oilseed crops grown worldwide. With significant expansion of acreage sown to canola during the past two decades, concern about blackleg, the most serious disease of canola, has increased (3,4). Blackleg disease is caused by Leptosphaeria maculans (Desmaz.) Ces. & De Not. (anamorph: Phoma lingam (Tode:Fr.) Desmaz.). The pathogen can ...

OBJECTIVE To assess the impact of outbreaks of Bordetella pertussis infection on a tertiary care medical system. DESIGN Retrospective study. SETTING Academic tertiary care medical center and affiliated ambulatory care settings. SUBJECTS All patients and healthcare workers (HCWs) who were in close contact with patients with laboratory-confirmed cases of B. pertussis infection from October ...

Mucormycosis is caused by the fungi belonging to order Mucorales. There has been an increasing trend of rising fungal infection during second wave COVID in India, seen among patients recovering from COVID-19. A 37-years-old middle-aged adult, with diagnosis left paranasal sinus mucormycosis, side pneumothorax (intercostal drainage tube in-situ) pneumonia reported emergency department (ED) COVID...

Test-taking skills are cognitive skills that enable students to undergo any test-taking situation in an appropriate manner. This study is aimed at assessing the relationship between students’ test-taking skills and each of the following variables: motivation to learn mathematics; mathematics anxiety; attitudes towards mathematics; and attitudes towards tests. The study was conducted on a random...