Primary squamous cell carcinoma of the colon is extremely rare. The etiology poorly understood, and currently, there are different hypotheses about origin this malignant neoplasm. Here, we r 87-year-old male with a moderately-differentiated nonkeratinizing colon.

Ffity-five patients suffering from second primary lung carcinoma, 10 synchronous and 45 after resection for lung carcinoma (metachronous), have been observed from 1400 resections. The first manifestation of a second carcinoma in this series has always been the appearance of a new shadow in the follow-up radiograph. In our experience, second primary lung carcinoma is a disease affecting only hea...

Introduction Presence of two primary malignancies is rare and occurs in 3-5% of the cancer patients. As per our extensive internet research, this is the only reported case of a synchronous sino-nasal embryonal rhabdomyosarcoma with squamous cell carcinoma-tongue. The case report is important because of the rare diagnosis and the challenge we faced in the diagnosis and treatment of the pat...

Liposarcoma is the name given to a group of soft tissue sarcomas (STSs) with adipocytic differentiation. As a group, liposarcomas are the second most common STSs in adults. In 1951 Kozonis et al published that in the English language only four cases of liposarcomas originating in the mediastinum had been described. Primary mediastinal liposarcoma is an uncommon neoplasm of intrathoracic origin....

Orbital lymphoma is very rare malignant neoplasm, usually diagnosed in early stage of disease as primary lymphoma, but dissemination occurs in approximately 33% of cases. Isolated bilateral adrenal lymphomatous involvement is extremely rare, described in 0.83% of cases. We present autopsy case of a 63-year-old man with bilateral orbital diffuse large cell lymphoma, clinical stage IEA, successfu...

The calreticulin gene has nine exons and most of the frequent mutations screened observed in 9th exon myeloproliferative neoplasm patients, especially essential thrombocythemia primary myelofibrosis. In current study, an uncommon mutation was a 51 y old man with polycythemia vera phenotype. Somatic novel homozygous affect 9 gene. These recent genetic variations were not reported previous studie...

Ovarian leiomyoma is a rare and incidentally detected neoplasm. It is usually reported in women of childbearing age. Clinically most patients are asymptomatic. Histopathologic examination is required to distinguish it from subserous leiomyomas and fibroma-thecoma group of ovarian tumors. We present 2 cases of ovarian leiomyoma along with brief review of literature. The first case of a 25 year o...

DNA restriction fragment length polymorphism analysis was carried out on a primary and recurrent hepatocellular carcinoma in a hepatitis B virus negative patient. For the primary tumour, allele losses were found on the short arm of chromosome 17 (probe: p144-D6, 17p13) and the long arm of chromosome 5 with the probe Lambda MS8 (5q35-qter); other probes showed either no allele loss or a non-info...

Spindle cell oncocytoma (SCO) is a rare and recently described neoplasm arising from the pituitary adenohypophysis thought to be derived from the folliculostellate cells. Even though SCO has been classified as a distinct World Health Organization (WHO) grade I tumor, sellar neoplasms with an oncocytic appearance are uncommon and have a wide differential diagnosis that includes primary and metas...