We examined the semantic impairment for natural kinds in patients with probable Alzheimer's disease (AD) and semantic dementia (SD) using an inductive reasoning paradigm. To learn about the relationships between natural kind exemplars and how these are distinguished from manufactured artifacts, subjects judged the strength of arguments such as "Humans have a chemical called sebum. Therefore, fr...

The study was conducted on ten volunteers. All of them developed blackish adherent material at the edges of the tape-covered areas after 48 hours. The glue used in micropore tape is made up of ultraviolet (UV)-cured acrylate polymers. [1] The tapes are non-expansible and the glue tends to move towards the periphery, and possibly beyond the margins of the tape due to stretching of the skin. The ...

BACKGROUND/AIM Systemic isotretinoin has been widely considered an effective and safe medical treatment for severe and refractory acne for nearly 3 decades. However, it also appears to cause undesirable cutaneous side effects. The aim of this study was to prospectively measure biophysical parameters of skin function among patients with acne vulgaris before and after 3 months of isotretinoin the...

flake (flk), an N-ethyl-N-nitrosourea-induced recessive germ line mutation of C57BL/6 mice, impairs the clearance of skin infections by Streptococcus pyogenes and Staphylococcus aureus, gram-positive pathogens that elicit innate immune responses by activating Toll-like receptor 2 (TLR2). Positional cloning and sequencing revealed that flk is a novel allele of the stearoyl coenzyme A desaturase ...

Recently, development and research of nutraceuticals based on marine collagen peptides (MCPs) have been growing due to their high homology with human collagens, safety, bioavailability through gut, and numerous bioactivities. The major concern regarding safety of MCPs intake relates to increased risk of oxidative stress connected with collagen synthesis (likewise in fibrosis) and to ROS product...

Comedones occur when an overproliferation of keratinocytes blocks sebum secretion in a pilosebaceous duct. Comedones have multiple possible etiologies and contributing factors. While comedones are common to acne, they are also seen in occupational exposures and are associated with certain syndromes. We describe a particularly rare case of comedones at the perianus that is not associated with an...

Effect of sebum and ointment rubbing was evaluated on the permeation of a model steroidal drug, triamcinolone acetonide (TA), from white petrolatum ointment through excised hairless rat skin. Two kinds of white petrolatum ointment containing TA at a concentration of 1.0% were made using a "pre-applied ointment," which was made by applying and recovering white petrolatum on and from the rat skin...

1. Indene has been administered to rabbits by stomach tube, and fractionation of ether extracts of the urine has yielded optically active c8and tran8-indane-1:2-diol in a total amount corresponding to about 5% of the dose. Acid treatment of the urine, either before or after ether extraction, yielded indan-2-one in amounts corresponding to about 25% of the dose of indene. 2. The same two diols h...

Background: Seborrheic dermatitis affects approximately 2 to 5% of the populace. Interestingly, the term ‘seborrheic dermatitis’ is somewhat a misnomer as there is no direct quantitative relationship between the degree of sebaceous activity and susceptibility to seborrheic dermatitis. Method: A pilot study was performed to initiate assessment of patient satisfaction with oral minocycline and to...