UNLABELLED Nesiritide is approved by Food and Drug Administration (FDA) for the treatment of patients with acute decompensated heart failure (ADHF) due its ability to rapidly reduce cardiac filling pressures and improve dyspnea. Numerous studies have shown that renal dysfunction is associated with unfavorable outcomes in patients with heart failure. In addition, there have been reports suggesti...

BACKGROUND The last decade has witnessed a sustained improvement of renal allograft survival that is partly explained by a better preservation of renal allograft function. This study describes time-dependent modifications of serum creatinine (SCr) during the first year after transplantation in the last decade in Spain and characterizes the predictive value of SCr on death-censored graft surviva...

BACKGROUND Chronic kidney disease (CKD) is a worldwide public health problem. Glomerular filtration rate (GFR) is accepted as the best way to diagnose and monitor kidney function. Plasma Cystatin C (CysC) has been proposed as a better marker of GFR than serum creatinine (SCr), but it is not widely used because of some drawbacks with CysC assays. Our purpose is to determine the diagnostic accura...

BACKGROUND Acute kidney injury (AKI) is a risk factor for long-term adverse outcomes, including acute myocardial infarction and death. However, the relationship between severity of AKI and in-hospital outcomes in the setting of acute myocardial infarction has not been well documented. METHODS AND RESULTS The study population (n = 59,970) was drawn from the Acute Coronary Treatment and Interve...

The promotion of Ag–ZSM-5 by cerium for the selective catalytic reduction (SCR) of NO with methane in the presence of an excess of oxygen was studied in this work. Ce–Ag–ZSM-5 catalyzes the CH4-SCR of NOx over the temperature range of 450–600◦C. Rate measurements of NO reduction to N2 under SCR conditions and of the competing CH4 oxidation by O2 (CH4 combustion) show that incorporation of a sma...

We present VLT/NACO SDI images of the very nearby star SCR 1845-6357 (hereafter SCR 1845). SCR 1845 is a recently discovered (Hambly et al. 2004) M8.5 star just 3.85 pc from the Sun (Henry et al. 2006). Using the capabilities of the unique SDI device, we discovered a substellar companion to SCR 1845 at a separation of 4.5 AU (1.170”±0.003” on the sky) and fainter by 3.57±0.057 mag in the 1.575 ...

BACKGROUND Contrast-induced acute kidney injury (CI-AKI) was traditionally defined as an increase in serum creatinine (sCr) after contrast media exposure. Recently, serum cystatin C (sCyC) has been proposed as an alternative to detect acute changes in renal function. The clinical implications of combining sCyC and sCr to diagnose CI-AKI remain unknown. METHODS AND RESULTS One thousand seventy...

The U.S. Environmental Protection Agency (EPA) performed an Information Collection Request (ICR) in 1999 to gather additional information on the control and emission of mercury from coal-fired power plants. The ICR data indicates that a significant, but highly variable, amount of mercury removal can occur across a power plant’s conventional air pollution control (APC) equipment used for the cap...