The susceptibility of Arvicanthis niloticus, Mastomys huberti, Mastomys erythroleucus and Mus musculus was studied to assess the capacity of these rodents to transmit Schistosoma mansoni. The susceptibility was determined by the percentage of adult schistosomes recovered, the number of eggs per gramme of faeces, the viability of these eggs and the capacity of the rodents to maintain the life cy...

Schistosomes undergo various morphological and metabolic changes during their development, reflected in a finely tuned regulation of protein and/or gene expression. The mechanisms involved in the control of gene expression during the development of the parasite are not understood. Two actin genes had been previously cloned and observed to be differentially expressed during the maturation of the...

BACKGROUND Chemotherapy for schistosomiasis has been around for 100 years. During the past century, great efforts have been made to develop new antischistosomal drugs from antimonials to nonantimonials, and some of these have been used extensively in clinical treatment. With the exception of a few drugs, such as oxamniquine and metrifonate, most of the antischistosomals developed in the pre-pra...

The sensitivity of the larval stages of Schistosoma mansoni to chemotherapy with praziquantel and oxamniquine was tested in mice during primary and secondary infections and after different intervals from cercarial exposure. Worm recovery by perfusion of the porto-mesenteric system, followed by counting and a morphometric study of the parasite, allowed the conclusion that the relative resistance...

The teguments of Schistosoma haematobium males from three localities in the Eastern Transvaal and one in the eastern Caprivi were studied by means of scanning electron microscopy. Eastern Transvaal S. haematobium, which occurs sympatrically with S. mattheei, a bovine schistosome also infecting man and which hybridizes with S. haematobium, exhibited certain S. mattheei characteristics. The occur...

Schistosoma spindale (Montgomery, 1906) has never been reported in Thailand, since this worm was discovered by Montgomery (1906) in two plain cattle (Bos indices) at Muktesar in India. Liston and Soparkar (1918) completed its life cycle in the goat infected with one kind of furcocercous cercariae obtained from a fresh water snail, Planorbis exustus (synonym of Indoplanorbis exustus). In 1960 an...

Antigenic communities were studied with sera from rabbits immunized with the Yamanashi and Chinese strains of Schistosoma japonicum eggs, and the antigens of five subspecies of Oncomelania snails, by immunoelectrophoresis. With regard to antigenic communities defined by the Yamanashi strain of S. japonicum eggs and Oncomelania snails, the schistosome egg produced 5 to 6 bands with Oncomelania h...