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As more children and adults become obese in the U.S. and other countries, obesity-associated diseases are becoming more prevalent worldwide (Poirier et al., 2006). Major chronic diseases linked to obesity include heart disease, stroke, and type 2 diabetes (Kahn et al., 2006; Poirier et al., 2006; Van Gaal et al., 2006). Thus, development of effective preventive and therapeutic strategies agains...

IntroductIon Beckers et al. (2006) published intriguing results, obtained in the rat fear conditioning paradigm, challenging classical associativist theories of learning. One of the main findings of Beckers et al. (2006) is that what they called subadditive pretraining abolished the expression of blocking (see Table 1; Figure 1), an effect that Beckers et al. (2005) had previously demonstrated ...

In this paper, we discuss a new generalization of univariate skew-Cauchy distribution with two parameters, we denoted this by GSC(&lambda1, &lambda2), that it has more flexible than the skew-Cauchy distribution (denoted by SC(&lambda)), introduced by Behboodian et al. (2006). Furthermore, we establish some useful properties of this distribution and by two numerical example, show that GSC(&lambd...

In embryonic stem cells (ESCs), silent genes with major developmental functions display a unique epigenetic state in which strong and broad binding by Polycomb repressive complexes (PRCs) is accompanied by the presence of poised RNA polymerase II (RNAPII) and activating histone marks (e.g. H3K4me3) (Azuara et al, 2006; Bernstein et al, 2006; Stock et al, 2007; Brookes et al, 2012). It has been ...

The pholyphenolic phytoalexin resveratrol (3,4 ́,5-trihydroxystilbene) is abundant in grape skins (with higher concentration in red as compared to white wine), peanuts, the roots of the weed Polygonum cuspidatum as well as in other fruits and vegetables (Cardile et al., 2007; Csaki et al., 2008). It is produced by plants in response to stress and has a wide range of pharmacological activities. R...

Imaging-guided thermal ablation using different energy sources (such as RF, microwave, or laser) continues to gain favor as a minimally invasive technique for the treatment of primary and metastatic hepatic malignant tumors (Ng et al., 2005; Pacella et al., 2005; Cabassa et al., 2006; Clasen et al., 2006; Shibata et al., 2006). Regardless of the primary energy source, all of these modalities in...