نتایج جستجو برای: saos 2

تعداد نتایج: 2525365  

Journal: :Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics 2017

Background: Cancer refers to the abnormal growth of cells and is still the most common cause of morbidity in world. The purpose of this study was to determine cytotoxicity effect of high molecular weight (HMWC) and low molecular weight of chitosan (LMWC) on three cancerous cell lines MCF-7, HeLa and Saos-2 with different histological origin. Methods: The anticancer property of two types of chi...

Introdution: The present study was conducted to evaluate the effect of miR-143 on the expression of Bcl2 gene at the level of mRNA, cell cytotoxicity in the SaOs-2 cell line (Osteosarcoma) and Hum 63 (Human primary bone cells). Methods: In this experimental study, miR-143 was introduced into the SaOs-2  and Hum 63 cell by the lipofectam 2000 system. Then, the effects of miR-143 on cytotoxicity...

Journal: :Archives of oral biology 2012
Bruno S Herrera Leila S Coimbra Alliny S Bastos Simone A Teixeira Joao P Steffens Marcelo N Muscara Luis C Spolidorio

OBJECTIVE The aim of this study was to investigate the effects of PRP on SAOS-2 cells in terms of cytokine expression, cell activity and oxidative stress. DESIGN Cell line SAOS-2 (1×10(5)cells/mL) were grown in culture medium α-MEM with 10% FBS for 24h and stimulated (or not) with PRP at concentrations of 3, 10 and 20%, LPS (E. coli, 10g/mL) and IL-1β (1mg/mL) for 24h. The supernatant was col...

2016
Axel Deing Thomas Ebel Regine Willumeit-Römer Hugo F. Lopez

Biomaterial surface functionalization remains of great interest in the promotion of cell osteogenic induction. Previous studies highlighted the positive effects of porous Ti-6Al-4V and phospholipid coating on osteoblast differentiation and bone remodeling. Therefore, the first objective of this study was to evaluate the potential synergistic effects of material porosity and phospholipid coating...

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