1 Department of Microbiology and Immunology, University of California, San Francisco, California, United States of America, 2 Diabetes Center, University of California, San Francisco, California, United States of America, 3 Innovative Genomics Institute, University of California, Berkeley, California, United States of America, 4 Biomedical Sciences Graduate Program, University of California, Sa...

*University of Puerto Rico School of Medicine, San Juan, Puerto Rico; Auxilio Mutuo Hospital, San Juan, Puerto Rico; †Auxilio Centro de Cáncer, Auxilio Mutuo Hospital, San Juan, Puerto Rico; University of Puerto Rico School of Medicine, San Juan, Puerto Rico; University of Texas, MD Anderson Cancer Center, Houston, Texas, United States of America; Moffitt Cancer Center, Tampa, Florida, United S...

From the Department of Medicine (L.T., K.L.H., D.T.O.) and the Center for Molecular Genetics (D.T.O.), University of California at San Diego, La Jolla; and the Veterans Affairs San Diego Healthcare System, San Diego, Calif. (L.T., K.L.H., D.T.O.). Address reprint requests to Dr. O’Connor at the Department of Medicine (9111H), University of California at San Diego, 3350 La Jolla Village Dr., San...

South African Centre for Epidemiological Modelling and Analysis (SACEMA), Stellenbosch University, Stellenbosch, South Africa; Public Health England, London, United Kingdom; Blood Systems Research Institute, San Francisco, CA; University of California, San Francisco, San Francisco, CA; University of California, San Diego, San Diego, CA; Department of Medical Affairs, International AIDS Vaccine ...

The aim of the study was to identify ion channel transcripts expressed in the sinoatrial node (SAN), the pacemaker of the heart. Functionally, the SAN can be divided into central and peripheral regions (center is adapted for pacemaking only, whereas periphery is adapted to protect center and drive atrial muscle as well as pacemaking) and the aim was to study expression in both regions. In rabbi...

The inhibitory action and the possible mechanism of anticancer compound Sanguinarine (SAN) on vascular endothelial growth factor (VEGF) in human mammary adenocarcinoma cells MCF-7 were evaluated in this study. We exposed MCF-7 to SAN for 24 h, then cell viability was assessed by using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction assay. Human VEGF was measured...

Neuronal modulation of the sinoatrial node (SAN) plays a crucial role in the initiation and maintenance of atrial arrhythmias (AF), although the exact mechanisms remain unclear. We used a computer model of a rabbit right atrium (RA) with a heterogeneous SAN and detailed ionic current descriptions for atrial and SAN myocytes to explore reentry initiation associated with autonomic activity. Heter...

(6 ) Swyt, C. R. Fiori, C. E. Microbeam Analysis-1986; San Francisco Press: San Francisco, CA, 1986; p 482. (7) Myklebust, R. L.; Marinenko, R. B.; Newbury, D. E.; Bright. D. S. Microbsem Analysis1985; Sen Francisco Press: San Francisco, CA, 1985; p 101. (6 ) Mayr, M.; Angeili, J. X-Ray Spectrom. 1985, 14, 89. (9) Ono, Y.; Nbken, C. H.; Tagata, S.; Seo, Y. Microbeam Anawsis1985; San Francisco P...

To investigate the effects of sanguinarine (SAN) on acute radiation induced injury in mice, 45 mice were randomly divided into control, 10 Gy and SAN+10 Gy groups. Mice in the 10 Gy and SAN+10 Gy groups were exposed to single X-ray radiation with an accumulated dose of 10 Gy. Mice in the SAN+10 Gy group were administered intraperitoneally with 2.5 mg/kg body weight of SAN before radiation. Five...