Despite extensive research during the last decades, coronary artery disease (CAD) remains the number one cause of death, responsible for near 50% of global mortality. A main reason for this is that CAD has a complex inheritance and etiology that unlike rare single gene disorders cannot fully be understood from studies of of genes one-by-one.In parallel, studies that simultaneously assess multip...

analysed for different diseases and sensitivity to medication. The results, which revealed risks of heart disease, diabetes and prostate cancer, could pave the way to similar tests for the general public.” The Daily Mirror on the same day was equally succinct, but at the same time both more and less informative: “A scientist has become the first person in the world to have his DNA screened. In ...

Hypertension affects 20% of the general population, and yet its etiologic basis remains unknown in the vast proportion of those affected.1 Hypertension greatly increases the risk of stroke, myocardial infarction, congestive heart failure and renal dysfunction thus making it an important focus of clinical research. Although pharmacological reductions in blood pressure have been shown to decrease...

Coronary artery disease (CAD) has a significant genetic contribution that is incompletely characterized. To complement genome-wide association (GWA) studies, we conducted a large and systematic candidate gene study of CAD susceptibility, including analysis of many uncommon and functional variants. We examined 49,094 genetic variants in ,2,100 genes of cardiovascular relevance, using a customise...

extended abstract 1. introduction abbasid period can be regarded as an epoch in which poetry and eulogy in persia reached maturity, i.e., in which poetry has become a means of praise and admiration (dayf, 2006, p. 565). the kings of this dynasty gathered a group of flattered eulogists and used them for political announcements (alebadi, 2006, p. 13), by allocating precious gifts of war booty to ...

Coronary artery disease (CAD) has a significant genetic contribution that is incompletely characterized. To complement genome-wide association (GWA) studies, we conducted a large and systematic candidate gene study of CAD susceptibility, including analysis of many uncommon and functional variants. We examined 49,094 genetic variants in ,2,100 genes of cardiovascular relevance, using a customise...

Pharmacy which is an art and science of preparing and dispensing drugs and Materia Medica gives the names, sources physical characters and chemical properties of herbs or substances used in medicine and their doses have been interwoven connected with medicine from the time immorial. This can be traced back to the findings of ancient Egyptian and Unani Physician like Hippocrates (460-377 B.C) Di...

The recently synthesized freestanding fouratom-thick double-layer sheet of ZnSe holds great promise as an ultraflexible and transparent photoelectrode material for solar water splitting. In this work, we report theoretical studies on a novel three-atom-thick single layer sheet of ZnSe that demonstrates a strong quantum confinement effect by exhibiting a large enhancement of the band gap (2.0 eV...