Correlation analysis based on chromatograms and pharmacological activities is essential for understanding the effective components in complex herbal medicines. In this report, HPLC and measurement of antioxidant properties were used to describe the active ingredients of Salvia miltiorrhiza injection (SMI). HPLC results showed that tanshinol, protocatechuic aldehyde, rosmarinic acid, salvianolic...

Phenolic diterpenes present in Rosmarinus officinalis and Salvia officinalis have anti-inflammatory and chemoprotective effects. We investigated the in vitro effects of carnosol (CL), carnosic acid (CA), carnosic acid-12-methylether (CAME), 20-deoxocarnosol and abieta-8,11,13-triene-11,12,20-triol (ABTT) in murine macrophages (RAW264.7 cells) and human chondrocytes. The substances concentration...

Herbal medicines and beverages have started to take an essential place in our daily lives. S. officinalis is one of the most used herbal tea species sage family. Secondary metabolites, especially oils, plays important role its biological properties. oil mostly rich camphor thujone, which these compounds could be toxicological. In present study, six spontaneous hybrid plants their parents were a...

Clinical studies have shown that several classes of antibiotics are evidenced in drug induced liver injury. The combination of amoxicillin with clavulanic acid is commonly cited in such cases. Accordingly, the present study investigated the potential hepatoprotective and in vivo antioxidant efficacy of sage essential oil in Co-amoxiclav induced hepatotoxicity in rats. Sage essential oil was hyd...

In our study, useful molecules in Rosmarinus officinalis ve Olea europaea have been purified. Rosmarinus officinalis is a rich source of active antioxidants. One of the most important bioactive molecules of those is rosmarinic acid. Rosmarinic acid has healing property in allergic inflammatory processes, is antitumoral, as well as has neuroprotective properties in chemical neurotoxicity and dif...

Sage (Salvia officinalis L.) is a popular herb which is native to the Mediterranean region and cultivated worldwide. Sage is an important source of antioxidants used as preservatives and has wider implications for the dietary intake of natural antioxidants.1,2 This antioxidant effect has been attributed to the main phenolic components, caffeic acid dimer – rosmarinic acid1 and flavonoids, being...