This study was undertaken to investigate the prokinetic activity of Unani herbomineral formulation (Dolabi) in streptozotocin induced diabetic rats and its in vitro antioxidant activity. Rat model of diabetes was established by intraperitoneal injection of streptozotocin (55 mg/kg, i.p). Rats were divided into three groups: Normal control, diabetic control and treatment groups. After two weeks ...

Objectives To retrospectively assess the influence of radical surgery following concurrent chemoradiotherapy (CCRT) on outcomes in cervical cancer (CC) patients. Methods Patients diagnosed with cervical squamous cell carcinoma or adenocarcinoma (FIGO stages IB2 to IIB) at the Yinbin Second People's Hospital between September 2008 and September 2013, were included in this study. Patients were ...

BACKGROUND Renal cell carcinoma (RCC) is a common malignancy of the urinary system with high rates of morbidity and mortality. OBJECTIVES This study aimed to investigate and analyze the clinical efficacy of retroperitoneal laparoscopic partial nephrectomy and laparoscopic radical nephrectomy for the treatment of small RCC. METHODS In this retrospective study of 45 patients with small RCC, t...

PURPOSE The proper indication for laparoendoscopic single-site surgery (LESS) in urology is still under debate, especially for malignant diseases. We compared the perioperative outcomes between LESS and conventional laparoscopy (CL) for upper urinary tract malignancies. MATERIALS AND METHODS We reviewed the records of 75 patients who underwent radical nephrectomy, nephroureterectomy with blad...

Three-step hand-assisted laparoscopic D2 radical gastrectomy (HALG) is a modified surgical procedure that has achieved satisfactory results for obese patients in our surgical center. To fully elucidate the advantages of this procedure, in this study, comprehensive and in-depth comparative analyses were performed to assess clinical data from obese gastric cancer patients who underwent HALG, lapa...

PURPOSE Elderly patients with rectal cancer are regarded as being at increased risk during radical resection because of lack of functional reserve and increased number of comorbidities. The aim of this study was to compare the short- and long-term outcomes of laparoscopic surgery with radical intent between elderly and young rectal cancer patients. METHODS Three-hundred ten patients who under...

Hydroxybenzylidene hydrazines exhibit a wide spectrum of biological activities. Here, we report synthesis and free radical scavenging activity of nine new N-(hydroxybenzylidene)-N'-[2,6-dinitro-4-(trifluoromethyl)]phenylhydrazines. The chemical structures of these compounds were confirmed by 1H-NMR, 13C-NMR, 19F-NMR, IR spectroscopy, LC-MS, and elemental analysis. The prepared compounds were te...

PURPOSE To report the 5-year oncological outcomes of patients undergoing laparoscopic radical nephrectomy for renal cancer compared to a cohort of patients undergoing open radical nephrectomy. METHODS We retrospectively analyzed the data of 88 patients undergoing radical nephrectomy for renal cell carcinoma prior to January 2000. Of these, 45 patients underwent laparoscopic radical nephrectom...