BACKGROUND Previously, we have observed that the isolated, erythrocyte-perfused rabbit heart has increased levels of heat-shock protein (HSP) 72 after a mild mechanical stress. We hypothesized that stretch-activated ion channels (SACs) mediated this increase. Methods and Results-- To test this hypothesis, we subjected isolated, perfused rat hearts to mechanical stretch. Gel mobility shift assay...

To determine whether ultrasonographic findings can predict the karyotype of spontaneous abortions, 137 pregnancies (54 spontaneous, 83 assisted ovulatory cycles) that subsequently aborted and had chromosome analysis performed on the products of conception were studied ultrasonographically. Transvaginal ultrasound was performed using an Acuson 128XP/10 with 7.5 MHz probe. The numbers of empty ge...

alpha-Fetoprotein (AFP) was shown to be the major secretory protein produced in vitro by normal rat yolk sacs. While not so active, AFP production was also detected in the transplantable tumors derived from normal yolk sacs. The major secretory protein synthesized by the tumor cells had a molecular weight of 40,000 and was reactive with an anti-rat albumin antibody. The functional messenger RNA...

MANIS, JAMES. Intestinal iron-transport defect in the mouse with sex-linked anemia. Am. J. Physiol. 220(l) : 135-139. 1971.-Everted duodenal gut sacs prepared from mice with sex-linked anemia (sZa) have a defect in the serosal transfer step of the active transport mechanism for iron that prevents the establishment of concentration gradients across the intestine greater than 1.0. The defect is p...

∗ S. Mok and K. Ong are currently Ph.D. and M.S. students of ECE at Northwestern University, Evanston, IL. Abstract An automatic method for generating assembly instructions using CAD files is presented in this paper. Algorithms for extracting geometrical information of objects stored in a non-proprietary format, ISO-10303, STEP-CAD data file are explained. The developed algorithms form an impor...

An effective technique of phase contrast synchrotron radiation computed tomography was established for the quantitative analysis of the microstructures in the respiratory zone of a mouse lung. Heitzman's method was adopted for the whole-lung sample preparation, and Canny's edge detector was used for locating the air-tissue boundaries. This technique revealed detailed morphology of the respirato...

Hypotonic cell swelling triggers an increase in intracellular Ca2+ concentration that is deemed responsible for the subsequent regulated volume decrease in many cells. To understand the mechanisms underlying this increase, we have studied the Ca2+ sources that contribute to hypotonic cell swelling-induced Ca2+ increase (HICI) in GH3 cells. Fura 2 fluorescence of cell populations revealed that e...

RESUMO Sistemas alagados construídos (SACs) são alternativas de engenharia para tratamento águas residuárias. Entretanto, ainda limitadas as pesquisas relacionadas à hidrodinâmica desses sistemas, quando comparados a outras unidades tratamento, como filtros biológicos, reatores anaeróbios, lagoas estabilização, dentre outros. Dessa forma, neste estudo teve-se objetivo avaliar o comportamento hi...

Single-atom catalysts (SACs) have attracted extensive interest owing to their maximized atomic utilization, low cost as well outstanding catalytic activity, selectivity, and stability for diverse applications. Due excellent performance in electrocatalysis, SACs can be applied electrochemical sensors, which been a predominant tool employed biosensing. In very recent studies, SAC-based biosensors...

Far from being a simple sensor, the retina actively participates in processing visual signals. One of the best understood aspects of this processing is the detection of motion direction. Direction-selective (DS) retinal circuits include several subtypes of ganglion cells (GCs) and inhibitory interneurons, such as starburst amacrine cells (SACs). Recent studies demonstrated a surprising complexi...