نتایج جستجو برای: s18
تعداد نتایج: 309 فیلتر نتایج به سال:
S18 Figure 1. N/OFQ inhibits chemoattractant-induced migration of lung mast cells and eosinophils. Migration of HMC-l cells (through an 8mm pore-size transwell membrane) was enhanced following stimulation With SCF (p<0.01, n = 5), CXCL10 (p<0.001, n = 5) and TNF-a stimulated ASM s/n (p<0.001, n = 8) and this was significantly inhibited by N/OFQ (p<0.01). HLMC migration induced by SCF (p<0.001, ...
An affinity chromatographic procedure, using ribosomal or tRNA covalently coupled to agarose through an adipic acid dihydrazide spacer, has been developed to isolate and identify the Escherichia coli ribosomal proteins which specifically bind to these RNA molecules. Transfer RNA, 5-S, 16-S and 23-S ribosomal RNA were readily immobilized on agarose-dihydrazide: the maximum amount coupled decreas...
Mouse p53 is phosphorylated at Ser18 and Ser23 after DNA damage. To determine whether these two phosphorylation events have synergistic functions in activating p53 responses, we simultaneously introduced Ser18/23 to Ala mutations into the endogenous p53 locus in mice. While partial defects in apoptosis are observed in p53S18A and p53S23A thymocytes exposed to IR, p53-dependent apoptosis is esse...
A 14-year-old patient with the complex congenital heart defect of transposition of great arteries, ventricular septal defect and pulmonary stenosis, after the "réparation à l'etage ventriculaire" operation at the age of 3, was admitted to the hospital with critical pulmonary stenosis with a maximal right ventricle-pulmonary artery (RV-PA) gradient of 110 mm Hg. Transcatheter pulmonary valve imp...
The expression levels of the two novel oncoproteins uridine-cytidine kinase like-1 (UCKL-1) and mitochondrial ribosomal protein S18-2 (MRPS18-2) were assessed in samples of hepatitis C virus (HCV)-associated hepatocellular carcinoma (HCC) using immunohistochemistry. Tissue microarray (TMA) paraffin blocks were prepared from 42 HCC tumor samples with the corresponding peri-tumor tissues and from...
Five different variants of L7/L12 containing single cysteine substitutions, two in the N-terminal (NTD) and three in the C-terminal domain (CTD), were produced, modified with [125I]N-[4-(p-azidosalicylamido)butyl]-3-(2'-pyridyldithio) propionamide ([125I]APDP), a sulfhydryl-specific, heterobifunctional, cleavable photo-cross-linking reagent, and reconstituted into ribosomes. These were irradiat...
Ten Italian globe artichoke clones belonging to the Romanesco typology were characterized in the western coastal area of Italy (Cerveteri, Rome), using a combination of morphological (UPOV descriptors), biochemical (HPLC analysis), and molecular (AFLP, ISSR, and SSR markers) traits. Significant differences among clones were found for many of the quantitative and qualitative morphological traits...
Abstract This study aimed at characterizing groundwater evolution using hydrogeochemical facies and signatures in two basins with contrasting climate geology, one the central part other eastern coast of Tanzania. The Kimbiji (humid, unconsolidated) aquifer is covered by an unconfined layer upper parts a confined lower parts, strong artesian flow characteristics while Singida (semi-arid, consoli...
سابقه و هدف: جداسازی RNA از گیاهانی که دارای مقدار زیادی ترکیبات پلیساکارید و پلیفنل میباشند به علت اتصال و رسوب این ترکیبات با RNA مشکل است. بنابراین در این مطالعه 11 پروتکل مختلف استخراجRNA از برگهای سیب غنی از ترکیبات فنلی مورد بررسی قرار گرفت. مواد و روش ها: کیفیت و کمیت RNAبا الکتروفورز ژل آگارز 1.2% و اسپکتروفتومتری نانودراپ در طول موج 230، 260 و 280 نانومتر تعیین شد و سنتز cDNA و...
Abstract Usability is regarded to be a fundamental requirement for in-vehicle HMIs, and usability evaluation reflects the impact of interface acceptance from users. This study introduced model AR-HUD by applying grey analytic hierarchy process (AHP). First, based on ameliorated PSSUQ (Post-Study System Questionnaire), system was modified optimized according characteristics AR-HUD. On this basis...
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