نتایج جستجو برای: s13
تعداد نتایج: 527 فیلتر نتایج به سال:
Our previous works revealed that human ribosomal protein S13 (RPS13) was up-regulated in multidrug-resistant gastric cancer cells and overexpression of RPS13 could protect gastric cancer cells from drug-induced apoptosis. The present study was designed to explore the role of RPS13 in tumorigenesis and development of gastric cancer. The expression of RPS13 in gastric cancer tissues and normal ga...
naling events that are continuously modified by environmental cues. However, the details of how these processes can change cell fate choices are still unknown. Previously, we demonstrated that sustained expression of HOXA3 both accelerated wound healing and promoted neovascularisation in diabetic mice. We have subsequently shown that in response to injury HOXA3 induces a significant increase in...
s13.m36.o3 Mogul: Rapid Retrieval of Molecular Geometry Information From a Crystallographic Database
The Cambridge Structural Database (CSD) currently contains over 310,000 structure determinations for small molecule organic and organometallic compounds, and thus is a good source of information on molecular geometries and conformational preferences. The program Mogul (Molecular Geometry Library) has been developed by the CCDC to provide rapid access to this information with full statistics. To...
Sirt1, an NAD-dependent protein deacetylase has emerged as important regulator of mammalian transcription in response to cellular metabolic status and stress1. Here we demonstrate that Sirt1 plays a neuroprotective role in models of Huntington’s disease (HD), an inherited neurodegenerative disorder caused by a glutamine repeat expansion in huntingtin protein2. Brainspecific knockout of Sirt1 re...
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