Recurrence of non-Hodgkin’s lymphoma more than 5 years after the initial diagnosis is rare. When late relapse occurs, it is difficult to determine whether it is a true recurrence or a new lesion. We experienced a case of an 81-year-old woman who developed central nervous system (CNS) lymphoma 12 years after remission of ocular adnexal lymphoma. Both showed the histology of diffuse large B-cell ...

Conflict of Interest: The authors of this paper have no conflicts of interest, including specific financial interests, relationships, and/or affiliations relevant to the subject matter or materials included. References 1. Roschewski M, Wilson WH. EBV-associated lymphomas in adults. Best Pract Res Clin Haematol 2012;25:75-89. 2. Niedobitek G. Epstein-Barr virus infection in the pathogenesis of n...

background: primary gastric lymphoma (pgl) is an uncommon malignancy with various histological subtypes and treatment outcomes. the aim of this study was to investigate the potential prognostic factors and clinicopathological characteristics of iranian patients with pgl. methods: the clinicopathological characteristics of 60 patients with pgl were retrospectively reviewed from 2001 to 2012. the...

Ibrutinib (USAN, also known as PCI-32765 and marketed under the name Imbruvica) (Figure 1) of formula C25H24N6O2 and molar mass 440.497 is an anticancer drug targeting B-cell malignancies. It was approved by the US Food and Drug Administration (FDA) in November 2013 for the treatment of mantle cell lymphoma and in February 2014 for the treatment of chronic lymphocytic leukemia. Ibrutinib is cur...