Background RV ejection fraction is the recognised marker of RV function although the assessment of deformation by strain analysis provides potential means for assessing early ventricular dysfunction before other recognised markers fall. RV strain analysis by tagging is time consuming and requires significant operator expertise due to the nature of the RV anatomy (particularly the thin free wall...

Right ventricular (RV) involvement after acute myocardial infarction (MI) carries an adverse prognosis, but in the majority of patients RV function recovers fully over time.1 It is believed that the lower oxygen requirement of the RV and higher collateral flow make the RV more resistant to ischemia. In the absence of infarction, myocardial ischemia leads to intracellular and subsequently extrac...

Pulmonary arterial hypertension (PAH) is often treated with endothelin (ET) receptor blockade or phosphodiesterase-5 (PDE5) inhibition. Little is known about the specific effects on right ventricular (RV) function and metabolism. We determined the effects of single and combination treatment with Bosentan [an ET type A (ET(A))/type B (ET(B)) receptor blocker] and Sildenafil (a PDE5 inhibitor) on...

Rotavirus (RV) and norovirus (NoV) are major causes of pediatric diarrhea and are altogether associated with approximately 800,000 deaths in young children every year. In Nicaragua, national RV vaccination program using the pentavalent RV5 vaccine from Merck was implemented in October 2006. To determine whether RV vaccination decreased the overall number of RV infections, we investigated the oc...

PURPOSE Rotavirus (RV) is a leading cause of severe gastroenteritis (GE) in children across the world. As there is a lack of epidemiological data for RV gastroenteritis (RVGE) in Saudi Arabia, this hospital-based study was designed to estimate the disease burden of RVGE and assess the prevalent RV types in Saudi children younger than 5 years of age. PATIENTS AND METHODS Children hospitalized ...

BACKGROUND Experimental data show that the right ventricle (RV) is more resistant to ischemia than the left ventricle. To date, limited data are available in humans because of the difficulty of discriminating reversible from irreversible ischemic damage. We sought to characterize RV ischemic injury in patients with reperfused myocardial infarction using cardiovascular magnetic resonance. METH...

Background—Experimental data show that the right ventricle (RV) is more resistant to ischemia than the left ventricle. To date, limited data are available in humans because of the difficulty of discriminating reversible from irreversible ischemic damage. We sought to characterize RV ischemic injury in patients with reperfused myocardial infarction using cardiovascular magnetic resonance. Method...

Results RV function measured by CMR was negatively correlated with peak systolic strain of mid RV free wall (P=0.038, Pearson r=-0.357) and also negatively correlated to both mean of strain (P=0.028, Pearson r=-0.376) and SR (P=0.035, Spearman’s rho=-0.362) of basal , mid and apical segments of RV. Conclusions Overall, in the assessment of RV function , echocardiographic measurement of strain a...

The right ventricular (RV) apex has been the standard pacing site since the development of implantable pacemaker technology. Although RV pacing was initially only utilized for the treatment of severe bradyarrhythmias usually due to complete heart block, today the indications for and implantation of RV pacing devices is dramatically larger. Recently, the adverse effects of chronic RV apical paci...

Carcinoid heart disease is a rare cause of heart failure with or without right valvular heart impairments. In this study, we showed a case of carcinoid tumour with hepatic metastases inducing carcinoid heart disease. Neuroendocrine heart involvement happens for severe tricuspid valve insufficiency and plaques on right ventricular (RV) walls produced by a release of serotonin (5-HT). A patient a...