Measurement of electronics and mechanics of single molecules provides a fundamental understanding of conductance as well as bonding at the atomic scale. To study the mechanics at these length scales, we have built a conducting atomic force microscope (AFM) optimized for high displacement and force resolution. Here, we simultaneously measure conductance and force across single Au-molecule-Au jun...

Zinc (Zn) is one of the most abundant metals and is essential for life. Through ligand interactions, often with thiolate from cysteine residues in proteins, Zn can play important structural roles in organizing protein structure and augmenting protein folding and stability. However, it is difficult to separate the contributions of Zn-ligand interactions from those originating from intrinsic prot...

Tomato is one of the sensitive fruits to mechanical impacts and physical tensions. The mostmechanical damages arise from handling which results in reducing tomato quality. in this study,impact energy effect has been studied in 3 different levels 0, 0.14 and 0.25 J by a pendulum impactapparatus, on changes of physicochemical properties of tomato, hybrid variety Shiva F1, includingripening factor...

The atomic force microscope was employed to investigate the time effect on normal interactions between a hydrophilic silica particle and an air bubble deposited onto a hydrophobic Teflon surface in pure water and 10 mM methyl isobutyl carbinol solutions. The force versus separation distance curves taken at different times after bubble generation were qualitatively compared. It has been found th...

Building pounding occurs between two adjacent buildings with small gap or without sufficient separation distance. It leads to damage buildings during earthquake due to impact. Many researchers have investigated building pounding based on impact force reduction and energy dissipation increase, when two buildings collide with each other. In numerical investigations, using specific link element, i...

Knowledge of the mechanical properties of electrospun fibers is important for their successful application in tissue engineering, material composites, filtration and drug delivery. In particular, electrospun collagen has great potential for biomedical applications due to its biocompatibility and promotion of cell growth and adhesion. Using a combined atomic force microscopy (AFM)/optical micros...

Tendons are known to have a profound impact on the overall function of the musculoskeletal system in their role as a structural link and force transmitter between muscle and bone. Their unique viscoelastic response under tension allows efficient use and recycling of stored energy during stretch involved in locomotion, modulating joint position control, and providing protection from muscle injur...

Aquaporins are integral membrane proteins from a larger family of major intrinsic proteins that formpores in the membrane of biological cells. Aquaporins form tetramers in the cell membrane with eachmonomer acting as a water channel.In this research, the AQP4 tetramer was modeled from its PDBstructure file, then, we have performed the intraction of aquaporin4 in different temperatures (298k,300...

The bacterial adhesive protein, FimH, is the most common adhesin of Escherichia coli and mediates weak adhesion at low flow but strong adhesion at high flow. There is evidence that this occurs because FimH forms catch bonds, defined as bonds that are strengthened by tensile mechanical force. Here, we applied force to single isolated FimH bonds with an atomic force microscope in order to test th...