Enzyme immunoassay (EIA) systems for measles virus and rubella virus were studied from the standpoints of requirements for suitable viral antigens and control antigens, and the sensitivity and specificity of the tests for detecting antibody elicited by past infection (determination of immunity status), and for serodiagnosis of currenet infections. Crude or semipurified measles virus antigens we...

OBJECTIVE To assess the suitability of using oral-fluid samples for determining the prevalence of immunity to vaccine-preventable infections. METHODS Paired blood and oral-fluid samples were obtained from 853 individuals of all ages from a rural Ethiopian community. Oral fluid around the gums was screened for measles- and rubella-specific antibodies using enhanced IgG antibody capture (GAC) e...

1043 have been due to direct trauma or haematoma around an aberrantly coursing hypoglossal nerve, we still consider high puncture of the internal jugular vein to be a useful approach. Immunity induced by rubella vaccines must persist throughout the childbearing years, a period of about 30 years. We have reported persistence of rubella antibody at values exceeding 15 000 IU/l in 89 4% of volunte...

E is a complex and severe neurological syndrome and the identification of its etiologic agents is useful to determine the treatment strategy and anticipate the illness course. However, according to many studies, the etiologic agent was not identified in 48-63% of encephalitis’ cases.1 Rubella is a rare etiologic agent, causing encephalitis only in one in 5000-6000 cases during previous epidemic...

Sera and CSFs of 85 patients with multiple sclerosis (MS), 49 patients with probable MS, and 165 control patients with other neurologic diseases were assayed for antibodies to rubella, mumps, measles, parainfluenza I (strain 6/94), herpes simplex, cytomegalovirus, varicella-zoster, and vaccinia viruses. Methods included complement fixation (CF), hemagglutination inhibition (HI), and complement-...

We successfully immunized the neonatal-onset multisystem inflammatory disease (NOMID) patient with live-attenuated vaccines for measles, rubella, varicella, and mumps and achieved sufficient antibody titer under canakinumab therapy without complications.

The results of testing for the presence of rubella antibody by haemagglutination inhibition in pregnant women are presented for a number of years, together with an analysis of results for the year 1977. Levels of immunity are correlated with age and British nationality. The influence of vaccine availability on numbers with antibody cannot be demonstrated nor can any evidence for the boosting of...