The standard management options were developed by a consensus committee and review panel of 26 experts to assist in providing optimal patient care based on the standard classification and grading systems for rosacea that were developed to perform research; analyze results and compare data from different sources; and provide a common terminology and reference for the diagnosis, treatment, and as...

Neurogenic inflammation is involved in skin inflammation. It is hypothesized that it is involved in the pathogenesis of the common chronic cutaneous vascular disorder rosacea, but the exact mechanism of action is currently unknown. Transient receptor potential vanilloid 1 (TRPV1) and ankyrin 1 (TRPA1) are widely expressed on primary sensory neuron endings and non-neuronal cells such as keratino...

INTRODUCTION Povidone iodine (PVP-I) 10% aqueous solution is a commonly utilized anti-septic employed for sterilization of the ocular surface prior to interventional procedures. Dimethylsulfoxide (DMSO) is a well-known skin penetration agent scarcely utilized in ophthalmic drug formulations. We describe here a low-dose formulation of 1% PVP-I (w/w) in a gel containing DMSO for use in the settin...

Rosacea is a field within dermatology with new insight within immunological research and new treatment-algorithm. Patient education on rosacea and appropriate treatments is an important aspect in helping patients succeed with therapy. Treatment should be tailored to each individual patient, taking into account: symptoms, trigger factors, patients' wishes, most bothersome symptoms, psychological...

Introduction: Rosacea is a chronic inflammatory dermatosis involving especially the cheeks, nose, chin and forehead, characterized by repetitive episodes of transient flushing or erythema, persistent in addition to phymatous changes, papules, pustules telangiectasias. Objective: detail current information related rosacea, description, presentation, epidemiology, pathophysiology, types, differen...

To the Editor: Kaposi’s varicelliform eruption (KVE) is a distinct viral skin disease which is characterized by disseminated vesiculopustules and erosions superimposed on the preexisting dermatosis. It is mostly caused by herpes simplex virus (HSV) type 1 or 2 and rarely by vaccine‐virus or Coxsackie A16 virus. The KVE is normally described in atopic dermatitis (AD), but also observed in associ...

Background Historically, rosacea treatments consisted of prescribing oral antibiotics, steroids, and isotretinoin, focusing more on the immediate eruption of the disease rather than the lasting vascular and fribrotic sequelea. More recently, Intense Pulse Light (IPL) has been shown to aid in the resolution of the vascular telangiectasia and general erythema. To this point, no modality has effec...

NEW DRUGS Mirvasco for Rosacea Brimonidine topical gel 0.33% (Mirvasco, Galderma) has been approved for the topical treatment of the facial erythema of rosacea in adults 18 years of age and older. Applied once daily, the medication reduces redness of the face and lasts up to 12 hours. An alpha2-adrenergic agonist, brimonidine appears to constrict the dilated facial blood vessels, which reduces ...

Rosacea is a common chronic cutaneous disorder that primarily occurs on the convex surfaces of the central face and is often characterized by exacerbations and remissions. A case of a 52-yr-old woman visited our clinic in February 2008 complaining typical features of rosacea including multiple pinhead to rice-sized erythematous papules. We applied various conventional treatments including topic...

INTRODUCTION Autosomal dominant chronic mucocutaneous candidiasis (CMC) without endocrinopathy (OMIM 114580) is a well-described entity. The associations recorded with this disorder to date are intercellular adhesion molecule-1 (ICAM-1) deficiency and hyper-immunoglobulin E syndrome. CLINICAL PICTURE We report a new association in a family (mother and nonidentical twin sons) where acne rosace...