Reactive oxygen species (ROS) are produced by host phagocytes and exert antimicrobial actions against a broad range of pathogens. The observable antimicrobial actions of ROS are highly dependent on experimental conditions. This perspective reviews recent controversies regarding ROS in Salmonella-phagocyte interactions and attempts to reconcile conflicting observations from different laboratories.

In a longitudinal study over a period of 21 months, we demonstrated that seminal reactive oxygen species (ROS) levels are independent of sperm concentration, motility, and abstinence duration within a healthy sperm donor, although some variations were observed in ROS levels. We suggest that fluctuation in seminal ROS values may be related to physiologic or transient changes in spermatogenesis.

Increased levels of reactive oxygen species (ROS) are associated with clinical varicoceles; however, its correlation with varicocele grade and testis size is unknown. In our study, seminal ROS levels showed significant correlation with left varicocele grade and significantly elevated seminal ROS levels were seen in men with left varicocele grade 2 and 3 compared to grade 1.

Reactive oxygen species (ROS) are involved in cell signaling, aging, and death and play a role in carcinogenesis. However, whether ROS are bystanders or active effectors of apoptosis was unclear until recently. New evidence shows that the killer lymphocyte protease granzyme B activates a conserved biochemical pathway centered on respiratory chain disruption to trigger mitocentric ROS-dependent ...

BACKGROUND A routine semen analysis is a first step in the laboratory evaluation of the infertile male. In addition, other tests such as measurement of reactive oxygen species can provide additional information regarding the etiology of male infertility. The objective of this study was to investigate the association of semen parameters with reactive oxygen species (ROS) in two groups: healthy d...

it   was   recently   demonstrated   that   5-(5-nitrofuran-2-yl)-1,   3,   4-thiadiazoles   with piperazinyl-linked benzamidine substituents are effective in vitro against leishmania major. following on this evidence, we used colorimetric assay of acid phosphatase activity in the promastigotes  as  an  indicator  for  cell  viability.  also  we  studied  the  effect  of  these compounds on ind...

Reactive oxygen species (ROS) are involved in physiological functions and act as mediators in various signaling processes. Elevated or sustained generation of free radicals and non radical species derived from free radicals can lead to an imbalance in the intracellular redox homeostasis. Normally, any excess levels of reactive radical and nonradical species generated are intercepted by antioxid...