نتایج جستجو برای: ror1

تعداد نتایج: 253  

2015
Abbas Ali Imani Fooladi Hamideh Mahmoodzadeh Hosseini Jafar Amani

BACKGROUND Today, Lack of efficient therapeutic strategy for breast cancer (the most common cause of death in women) is one of the momentous problematic topics for all health care committees. Designing new specific vaccine, based on antigens located on the surface of cancer cells can be useful. Over expression of ROR1, lacked of HER2/neu, and hormone receptors on cell surface in the breast canc...

Journal: :American journal of human genetics 2016
Lixing Yang Mi-Sook Lee Hengyu Lu Doo-Yi Oh Yeon Jeong Kim Donghyun Park Gahee Park Xiaojia Ren Christopher A Bristow Psalm S Haseley Soohyun Lee Angeliki Pantazi Raju Kucherlapati Woong-Yang Park Kenneth L Scott Yoon-La Choi Peter J Park

Although exome sequencing data are generated primarily to detect single-nucleotide variants and indels, they can also be used to identify a subset of genomic rearrangements whose breakpoints are located in or near exons. Using >4,600 tumor and normal pairs across 15 cancer types, we identified over 9,000 high confidence somatic rearrangements, including a large number of gene fusions. We find t...

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