BACKGROUND Somatic afferent nerve stimuli are used for treating an overactive bladder (OAB), a major cause of nocturia in the elderly. Clinical evidence for this treatment is insufficient because of the lack of appropriate control stimuli. Recent studies on anesthetized animals show that gentle stimuli applied to perineal skin with a roller could inhibit micturition contractions depending on th...

We measured aortic flow by two-dimensional Doppler echocardiography in an open-chest dog model to examine how variations in Doppler sample volume length and position influence aortic hemodynamic flow calculations. Fourteen dogs underwent right-heart bypass, in which venous return from the venae cavae drained by gravity to a reservoir. A variable-speed roller pump returned the blood to the pulmo...

In a hydraulic jump, the turbulent flow region between the upstream supercritical flow and downstream subcritical flow is called the jump roller. The turbulence development in the jump roller leads to substantial energy dissipation as well as free-surface fluctuations, oscillations of jump position, air entrainment and unstationary velocity field. The time scales of these motions cover a broad ...

Vacuum-assist venous drainage (VAVD) can increase venous blood return during cardiopulmonary bypass (CPB) procedures. However, the negative pressure created in the closed cardiotomy reservoir can be transmitted to the oxygenator if a nonocclusive or centrifugal arterial pump is used, resulting in bubble transgression (BT) from the gas to blood compartment of the oxygenator. We analyzed the vacu...

Forced hydraulic jump in a horizontal stilling basin with one and two continuous sills at the downstream end of an ogee standard weir was investigated. Experiments were completed on sills of five different heights which were fixed at two different distances from the toe of the weir. The main characteristics of the jump such as the sequent depth ratio, relative roller length, and relative ener...

In order to improve the service life of needle roller bearing used in a precision cycloid reducer, and reveal skew collision phenomenon bearing, based on force analysis transmission mechanism reducer considering friction between wheel, roller, cage, crank shaft, dynamic contact rolling bodies is simulated by Hertz elastic contact, where cage pocket hole equivalent spring damping, nonlinear mode...

The feasibility of a purified, inactivated dengue (DEN) vaccine made in Vero cells was explored. A DEN-2 virus candidate was chosen for production of a monotypic, purified, inactivated vaccine (PIV). Virus was harvested from roller bottle culture supernatants, concentrated, and purified on sucrose gradients. The purified virus was inactivated with 0.05% formalin at 22 degrees C. After inactivat...

This study investigated changes in technique and efficiency after high-intensity exercise to exhaustion in elite cross-country skiers. Twelve elite male skiers completed 4 min submaximal exercise before and after a high-intensity incremental test to exhaustion with the G3 skating technique on a 5% inclined roller-ski treadmill. Kinematics and kinetics were monitored by instrumented roller skis,...