نتایج جستجو برای: roflumilast

تعداد نتایج: 449  

Journal: :Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation 2017

2017
Floriane Montanari Anna Cseke Katrin Wlcek Gerhard F. Ecker

The breast cancer resistance protein (BCRP) is an ABC transporter playing a crucial role in the pharmacokinetics of drugs. The early identification of substrates and inhibitors of this efflux transporter can help to prevent or foresee drug-drug interactions. In this work, we built a ligand-based in silico classification model to predict the inhibitory potential of drugs toward BCRP. The model w...

2006
Wei Zhu Tony Chan

We propose a new variational model for image denoising, which employs mean curvature information of the image surface (x, f(x)) induced by the given image f : Ω → R. Besides removing noise efficiently and preserving edges of objects, our method can also keep corners of objects as well as grey-scale intensity contrasts of images. We also compare our model with the classical ROF model [18].

Journal: :International Journal of Chronic Obstructive Pulmonary Disease 2011

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