نتایج جستجو برای: robertsonian translocation

تعداد نتایج: 47030  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2017
Jiawei Xu Zhen Zhang Wenbin Niu Qingling Yang Guidong Yao Senlin Shi Haixia Jin Wenyan Song Lei Chen Xiangyang Zhang Yihong Guo Yingchun Su Linli Hu Jun Zhai Yile Zhang Fangli Dong Yumei Gao Wenhui Li Shiping Bo Mintao Hu Jun Ren Lei Huang Sijia Lu X Sunney Xie Yingpu Sun

Reciprocal translocations (RecT) and Robertsonian translocations (RobT) are among the most common chromosomal abnormalities that cause infertility and birth defects. Preimplantation genetic testing for aneuploidy using comprehensive chromosome screening for in vitro fertilization enables embryo selection with balanced chromosomal ploidy; however, it is normally unable to determine whether an em...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2001
S Garagna N Marziliano M Zuccotti J B Searle E Capanna C A Redi

In mammals, Robertsonian (Rb) translocation (the joining of two telo/acrocentric chromosomes at their centromere to form a metacentric) is the most effective process in chromosomal evolution leading to speciation; its occurrence also affects human health (through the induction of trisomies) and the fertility of farm animals. To understand the mechanism of Rb translocation, we used the house mou...

Journal: :Turkish journal of medical sciences 2015
Nagwa E A Gaboon Ahmed Ramy Mohamed Solaf M Elsayed Osama K Zaki Mohamed A Elsayed

BACKGROUND/AIM To evaluate the incidence of chromosomal abnormalities in couples who experience recurrent abortion and identify additional factors that may be predictive of abortion, such as parental age and unfavorable obstetric or abnormal semen analysis. MATERIALS AND METHODS The present study examined 125 couples who had experienced recurrent abortion. All subjects provided a detailed per...

2014
B. Xiong K. Tan Y.Q. Tan F. Gong S.P. Zhang C.F. Lu K.L. Luo G.X. Lu G. Lin

Translocation is one of the more common structural rearrangements of chromosomes, with a prevalence of 0.2%. The two most common types of chromosomal translocations, Robertsonian and reciprocal, usually result in no obvious phenotypic abnormalities when balanced. However, these are still associated with reproductive risks, such as infertility, spontaneous abortion and the delivery of babies wit...

Journal: :Folia histochemica et cytobiologica 2015
Ewa Pastuszek Jolanta Kiewisz Patrycja M Kulwikowska Mariusz Lukaszuk Krzysztof Lukaszuk

INTRODUCTION Somatic chromosomal rearrangements that occur in infertile males are thought to be one of the major genetic factors influencing male infertility. The objective of this retrospective study was to evaluate sperm parameters in a group of patients with balanced translocations. MATERIAL AND METHODS We analyzed semen of 84 balanced somatic translocation carriers [35 Robertsonian transl...

2015
Haixian Zhan Xiaojun Zhang Guangrong Li Zhihui Pan Jin Hu Xin Li Linyi Qiao Juqing Jia Huijuan Guo Zhijian Chang Zujun Yang

A new wheat-Thinopyrum translocation line CH13-21 was selected from the progenies derived from a cross between wheat-Th. intermedium partial amphiploid TAI7047 and wheat line Mianyang11. CH13-21 was characterized by using genomic in situ hybridization (GISH), multicolor-GISH (mc-GISH), multicolor-fluorescence in situ hybridization (mc-FISH) and chromosome-specific molecular markers. When inocul...

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