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Recombinant inbred (RI) strains are useful in linkage analysis and gene mapping. However, the generally small number of strains in an RI strain set limits the power of RI strains in linkage detection. Several methods for increasing the power of RI strains have been used, including summing data across RI strain sets and excluding linkage to genomic regions. In this paper, Bayesian analysis is ap...

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Abstrak: Data memiliki peran penting dalam pengambilan keputusan strategis. Oleh karenanya, pihak yang mampu mengolah dan memanfaatkan data-data tersedia volume besar, keragaman variatif, kompleksitas tinggi kecepatan penambahan data tinggi, dapat mengambil keuntungan besar. Penggunaan metode prototyping di penelitian ini bertujuan agar peneliti mendapatkan gambaran aplikasi akan dibangun melal...

BACKGROUND AND AIM Chronic kidney disease (CKD) is frequent in type 2 diabetes mellitus (T2DM), and therapeutic management of diabetes is more challenging in patients with renal impairment (RI). The place of metformin is of particular interest since most scientific societies now recommend using half the dosage in moderate RI and abstaining from use in severe RI, while the classic contraindicati...

The purpose of this study was to assess the effect of different rest intervals (RI) between sets on number of repetitions, sustainability of repetitions, and total volume during a leg press exercise. Seventeen resistance-trained older women (68.0 ± 5.9 years, 71. 2 ± 11.7 kg, 1.58 ± 0.07 m) participated in the study. All participants performed three sets to voluntary exhaustion, with loads that...

BACKGROUND The association between baseline renal impairment (RI) and the prognosis of diffuse large B-cell lymphoma (DLBCL) was previously not defined. The aim of this study was to evaluate the prognostic value of RI in patients with DLBCL treated with three-weekly rituximab plus cyclophosphamide, Adriamycin, vincristine, and prednisolone immunochemotherapy (R-CHOP21). METHODS Patients with ...

Retro-inverso (ri) analogs of model T cell and B cell epitopes were predictively designed as mimics and then assayed for activity to understand the basis of functional ri-antigenic peptide mimicry. ri versions of two MHC class I binding peptide epitopes, one from a vesicular stomatitis virus glycoprotein (VSV(p)) and another from OVA (OVAp), exhibit structural as well as functional mimicry of t...

In the present study, numerical simulations are performed to identify role of Reynolds number (Re), Richardson (Ri) and free-stream orientations (α) on flow structures, aerodynamic parameters heat transfer characteristics for conditions (20 ≤ Re 120, 0° α 90° 0 Ri 1.6). Prandtl (Pr) cylinder orientation (ϕ) kept fixed at 0.71 0°. The Oberbeck–Boussinesq approximation is used account buoyancy ef...

This paper carefully considers random landscapes related to Kauffman’s NK model. In particular, it considers a superset of this model (the NKP model) recently suggested in the GA-analytic literature. Landscapes are exhaustively examined for both the distribution of local optima relative to the global optima, and for characteristics that would effect juxtapositional (building block based) search...