Seven stilbenes and one catechin were bioactivity-guidedly isolated from the rhizomes of Rheum palmatem. Their structures were identified as piceatannol (1), resveratrol (2), piceid (3), rhapontigenin (4), piceatannol-3´-O-β-D-glucopyranoside (5), rhaponticin (6), catechin (7) and desoxyrhapontigenin (8). Anti-monoamine oxidase (MAO) activities of compounds 1-8 were tested. Compounds 1 and 8 sh...

The aim of the study is to evaluate ethanol extract Rheum ribes root (RTE), as well and young shoots (RYSE), for its chemical composition, antioxidant properties cytotoxic effects. Total polyphenols (TPC), total flavonoid (TFC), radical scavenging activity (DPPH), ferric reducing power (FRAP) extracts were determined using colorimetric methods. Mineral contents vitamin values samples by ICP-MS ...

Rhapontin was purified from a methanol extract from the roots of Rheum undulatum, and rhapontigenin was produced by an enzymatic transformation of rhapontin. Rats were fed a high-cholesterol diet to induce hyperlipidemia, followed by oral treatment with rhapontin or rhapontigenin (1-5 mg/kg/day). Rhapontin and rhapontigenin treatment resulted in a significant (p<0.05) dose-dependent decrease in...

Hydroxyanthraquinones represent a group of pharmacologically active compounds characteristic for plants of the Rumex and Rheum genera. These compounds in the human intestine act as laxative compounds. As they cause the greatest side effects and are often abused by the public, their accurate analysis in plants and plant-derived laxatives is much needed. To isolate compounds from plants, pressuri...

Rheum ribes is among the Polygonaceae family which is endemic in Iran and a few neighboring countries. In this investigation, antibacterial effects of root, stalk and leaves extracts of Rheum ribes on a few common clinical isolates of gram negative pathogens were studied, using the cup plate and paper disc methods. Gram negative microorganisms studied were Escherichia coli, Klebsiella pneumonia...