Objective: The present investigation is aimed to develop and validate, a simple, consistent sensitive stability-indicating reverse phase-high performance liquid chromatography (RP-HPLC) method for the determination of oral anti-diabetic drug Canagliflozin in bulk pharmaceutical dosage form as per International Council Harmonization Technical Requirements Pharmaceuticals Human Use (ICH-Q2 (R1))....

In this article, ZnO and ZnO:Mn nanoparticles prepared by reverse micelle method. The various crystalline properties of these nanoparticles such as size, d-spacing, strain, stress, dislocation density and texture coefficient have been calculated with the help of XRD spectrum. The XRD results indicated that the synthesized ZnO and ZnO:Mn nanoparticles have a pure wurtzite (hexagonal phase) struc...

Two UV-spectrophotometric and one reverse phase high performance liquid chromatography methods have been developed for the simultaneous estimation of amlodipine besilate, losartan potassium and hydrochlorothiazide in tablet dosage form. The first UV spectrophotometric method was a determination using the simultaneous equation method at 236.5, 254 and 271 nm over the concentration range 5-25, 10...

In a recent experiment, Foster and Wilson [1] have observed reverse replay of behavioral sequences in rodents’ hippocampal place cells during non-running awake state in coincidence with sharp waves. In this paper, to elucidate this reverse replay mechanism, a theta phase precession computational model is assumed in one time trial learning experiment of a behavioral sequence. Our simulations dem...

Diosmin and hesperidin are natural flavonoid glycosides found in various plant materials, mainly in citrus fruits in different concentrations. Diosmin for pharmaceutical use is obtained mainly semi-synthetically from hesperidin. Hesperidin often accompanies diosmin as a natural impurity in different pharmaceutical formulations; therefore, a simple, fast and precise method for the simultaneous a...

This research paper describes simple, specific, accurate and precise reverse phase high pressure liquid chromatographic method for the simultaneous determination of Montelukast sodium and Bambuterol hydrochloride in combined dosage form. The sample was analyzed by reverse phase C18 column (Phenomenex C18, 5μ, 250mm x 4.6mm) as stationary phase; methanol: acetonitrile : 1% trichloroacetic acid i...

We propose a novel type of cascading parametric interaction for generating a nonlinear phase shift in dielectric media with a quadratic nonlinear response based on two-frequency wave mixing of the fundamental and second-harmonic waves. Self-phase modulation of the fundamental wave results from a cascading process consisting of four second-order subprocesses, the direct and reverse subprocesses ...